Nebacumab ?
Monoclonal antibody
Type Whole antibody
Source Human
Target endotoxin
Clinical data
AHFS/ International Drug Names
Pregnancy cat.  ?
Legal status  ?
CAS number 138661-01-5 N
ATC code J06BC01
KEGG D05126 YesY
Chemical data
Formula  ?
 N(what is this?)  (verify)

Nebacumab is a human monoclonal antibody developed for the treatment of sepsis.[1] It has been withdrawn in 1993 because it failed to reduce mortality in clinical trials.[2]


  1. ^ Derkx, B.; Wittes, J.; McCloskey, R. (1999). "Randomized, Placebo‐Controlled Trial of HA‐1A, a Human Monoclonal Antibody to Endotoxin, in Children with Meningococcal Septic Shock". Clinical Infectious Diseases 28 (4): 770–726. doi:10.1086/515184. PMID 10825037.  edit
  2. ^ WHO: Consolidated List of Products