Interleukin-17 receptor

Interleukin-17 receptor

protein
Name = interleukin 17 receptor A
caption =


width =
HGNCid = 5985
Symbol = IL17RA
AltSymbols = IL17R, CDw217
EntrezGene = 23765
OMIM = 605461
RefSeq = NM_014339
UniProt = Q96F46
PDB =
ECnumber =
Chromosome = 22
Arm = q
Band = 11.1
LocusSupplementaryData =
protein
Name = interleukin 17 receptor B
caption =


width =
HGNCid = 18015
Symbol = IL17RB
AltSymbols = IL17BR
EntrezGene = 55540
OMIM = 605458
RefSeq = NM_172234
UniProt = Q9NRM6
PDB =
ECnumber =
Chromosome = 3
Arm = p
Band = 21.1
LocusSupplementaryData =
protein
Name = interleukin 17 receptor C
caption =


width =
HGNCid = 18358
Symbol = IL17RC
AltSymbols = IL17-RL
EntrezGene = 84818
OMIM = 610925
RefSeq = NM_032732
UniProt = Q8NAC3
PDB =
ECnumber =
Chromosome = 3
Arm = p
Band = 25.3
LocusSupplementaryData =
protein
Name = interleukin 17 receptor D
caption =


width =
HGNCid = 17616
Symbol = IL17RD
AltSymbols = SEF, IL17RLM, FLJ35755, IL-17RD
EntrezGene = 54756
OMIM = 606807
RefSeq = NM_017563
UniProt = Q8NFM7
PDB =
ECnumber =
Chromosome = 3
Arm = p
Band = 21.1
LocusSupplementaryData =
protein
Name = interleukin 17 receptor E
caption =


width =
HGNCid = 18439
Symbol = IL17RE
AltSymbols = FLJ23658
EntrezGene = 132014
OMIM =
RefSeq = NM_153480
UniProt = Q8NFR9
PDB =
ECnumber =
Chromosome = 3
Arm = p
Band = 25.3
LocusSupplementaryData =
protein
Name = interleukin 17 receptor E-like
caption =


width =
HGNCid = 33808
Symbol = IL17REL
AltSymbols =
EntrezGene = 400935
OMIM =
RefSeq = NM_001001694
UniProt = Q6ZVW7
PDB =
ECnumber =
Chromosome = 22
Arm = q
Band = 13.33
LocusSupplementaryData =

Interleukin-17 receptor (IL-17R) is a cytokine receptor which binds interleukin 17.cite journal | author = Yao Z, Spriggs MK, Derry JM, Strockbine L, Park LS, VandenBos T, Zappone JD, Painter SL, Armitage RJ | title = Molecular characterization of the human interleukin (IL)-17 receptor | journal = Cytokine | volume = 9 | issue = 11 | pages = 794–800 | year = 1997 | pmid = 9367539 | doi = 10.1006/cyto.1997.0240 | issn = ] Functional IL-17R is a heteromeric complex consisting of at least IL17RA and IL17RC.cite journal | author = Toy D, Kugler D, Wolfson M, Vanden Bos T, Gurgel J, Derry J, Tocker J, Peschon J | title = Cutting edge: interleukin 17 signals through a heteromeric receptor complex | journal = J. Immunol. | volume = 177 | issue = 1 | pages = 36–9 | year = 2006 | pmid = 16785495 | doi = | issn = | url = http://www.jimmunol.org/cgi/content/abstract/177/1/36 ]

A number of additional variants exist including IL17RB,cite journal | author = Tian E, Sawyer JR, Largaespada DA, Jenkins NA, Copeland NG, Shaughnessy JD | title = Evi27 encodes a novel membrane protein with homology to the IL17 receptor | journal = Oncogene | volume = 19 | issue = 17 | pages = 2098–109 | year = 2000 | pmid = 10815801 | doi = 10.1038/sj.onc.1203577 | issn = ] which binds preferentially IL17B and IL17E.cite journal | author = Shi Y, Ullrich SJ, Zhang J, Connolly K, Grzegorzewski KJ, Barber MC, Wang W, Wathen K, Hodge V, Fisher CL, Olsen H, Ruben SM, Knyazev I, Cho YH, Kao V, Wilkinson KA, Carrell JA, Ebner R | title = A novel cytokine receptor-ligand pair. Identification, molecular characterization, and in vivo immunomodulatory activity | journal = J. Biol. Chem. | volume = 275 | issue = 25 | pages = 19167–76 | year = 2000 | pmid = 10749887 | doi = 10.1074/jbc.M910228199 | issn = ] cite journal | author = Lee J, Ho WH, Maruoka M, Corpuz RT, Baldwin DT, Foster JS, Goddard AD, Yansura DG, Vandlen RL, Wood WI, Gurney AL | title = IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1 | journal = J. Biol. Chem. | volume = 276 | issue = 2 | pages = 1660–4 | year = 2001 | pmid = 11058597 | doi = 10.1074/jbc.M008289200 | issn = ]

References

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