- GNB4
Guanine nucleotide binding protein (G protein), beta polypeptide 4, also known as GNB4, is a human
gene .cite web | title = Entrez Gene: GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=59345| accessdate = ]PBB_Summary
section_title =
summary_text = Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors.cite web | title = Entrez Gene: GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=59345| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Downes GB, Gautam N |title=The G protein subunit gene families. |journal=Genomics |volume=62 |issue= 3 |pages= 544–52 |year= 2000 |pmid= 10644457 |doi= 10.1006/geno.1999.5992
*cite journal | author=Pietruck F, Moritz A, Montemurro M, "et al." |title=Selectively enhanced cellular signaling by Gi proteins in essential hypertension. G alpha i2, G alpha i3, G beta 1, and G beta 2 are not mutated. |journal=Circ. Res. |volume=79 |issue= 5 |pages= 974–83 |year= 1996 |pmid= 8888689 |doi=
*cite journal | author=Asano T, Morishita R, Ueda H, Kato K |title=Selective association of G protein beta(4) with gamma(5) and gamma(12) subunits in bovine tissues. |journal=J. Biol. Chem. |volume=274 |issue= 30 |pages= 21425–9 |year= 1999 |pmid= 10409705 |doi=
*cite journal | author=Huang L, Shanker YG, Dubauskaite J, "et al." |title=Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium. |journal=Nat. Neurosci. |volume=2 |issue= 12 |pages= 1055–62 |year= 2000 |pmid= 10570481 |doi= 10.1038/15981
*cite journal | author=Evanko DS, Thiyagarajan MM, Siderovski DP, Wedegaertner PB |title=Gbeta gamma isoforms selectively rescue plasma membrane localization and palmitoylation of mutant Galphas and Galphaq. |journal=J. Biol. Chem. |volume=276 |issue= 26 |pages= 23945–53 |year= 2001 |pmid= 11294873 |doi= 10.1074/jbc.M101154200
*cite journal | author=Ruiz-Velasco V, Ikeda SR, Puhl HL |title=Cloning, tissue distribution, and functional expression of the human G protein beta 4-subunit. |journal=Physiol. Genomics |volume=8 |issue= 1 |pages= 41–50 |year= 2002 |pmid= 11842130 |doi= 10.1152/physiolgenomics.00085.2001
*cite journal | author=Huang L, Max M, Margolskee RF, "et al." |title=G protein subunit G gamma 13 is coexpressed with G alpha o, G beta 3, and G beta 4 in retinal ON bipolar cells. |journal=J. Comp. Neurol. |volume=455 |issue= 1 |pages= 1–10 |year= 2003 |pmid= 12454992 |doi= 10.1002/cne.10396
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Cuello F, Schulze RA, Heemeyer F, "et al." |title=Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta. |journal=J. Biol. Chem. |volume=278 |issue= 9 |pages= 7220–6 |year= 2003 |pmid= 12486123 |doi= 10.1074/jbc.M210304200
*cite journal | author=Sprague RS, Bowles EA, Olearczyk JJ, "et al." |title=The role of G protein beta subunits in the release of ATP from human erythrocytes. |journal=J. Physiol. Pharmacol. |volume=53 |issue= 4 Pt 1 |pages= 667–74 |year= 2003 |pmid= 12512701 |doi=
*cite journal | author=Rosskopf D, Nikula C, Manthey I, "et al." |title=The human G protein beta4 subunit: gene structure, expression, Ggamma and effector interaction. |journal=FEBS Lett. |volume=544 |issue= 1-3 |pages= 27–32 |year= 2003 |pmid= 12782285 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504PBB_Controls
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