- NME1-NME2
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NME1-NME2 readthrough 
PDB rendering based on 1be4.Available structures PDB 1NSK, 1NUE, 3BBB, 3BBC, 3BBF Identifiers Symbols NME1-NME2; FLJ93990; NM23-LV; NMELV External IDs MGI: 3648428 HomoloGene: 86776 GeneCards: NME1-NME2 Gene EC number 2.7.4.6 Gene Ontology Sources: Amigo / QuickGO Orthologs Species Human Mouse Entrez 654364 433968 Ensembl n/a ENSMUSG00000062499 UniProt P22392 n/a RefSeq (mRNA) NM_001018136.2 XM_485703 RefSeq (protein) NP_001018146 XP_485703 Location (UCSC) n/a Chr 5:
149.93 – 149.93 MbPubMed search [1] [2] NM23-LV, also known as NME1-NME2, is a human gene.[1]
The NME1-NME2 mRNA is a naturally occurring co-transcribed product of the neighboring NME1 and NME2 genes. The significance of this co-transcribed mRNA and the function of its predicted protein product have not yet been determined. Alternative splicing of this gene results in different transcript variants encoding distinct isoforms, but the full-length nature of each variant has not been defined.[1]
References
Further reading
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Valentijn LJ, Koster J, Versteeg R (2006). "Read-through transcript from NM23-H1 into the neighboring NM23-H2 gene encodes a novel protein, NM23-LV.". Genomics 87 (4): 483–9. doi:10.1016/j.ygeno.2005.11.004. PMID 16442775.
PDB gallery 
1be4: NUCLEOSIDE DIPHOSPHATE KINASE ISOFORM B FROM BOVINE RETINA
1bhn: NUCLEOSIDE DIPHOSPHATE KINASE ISOFORM A FROM BOVINE RETINA
1jxv: Crystal Structure of Human Nucleoside Diphosphate Kinase A
1nsk: THE CRYSTAL STRUCTURE OF A HUMAN NUCLEOSIDE DIPHOSPHATE KINASE, NM23-H2
1nue: X-RAY STRUCTURE OF NM23 HUMAN NUCLEOSIDE DIPHOSPHATE KINASE B COMPLEXED WITH GDP AT 2 ANGSTROMS RESOLUTION
2hvd: Human nucleoside diphosphate kinase A complexed with ADP
2hve: S120G mutant of human nucleoside diphosphate kinase A complexed with ADP
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