GNB2

GNB2

Guanine nucleotide binding protein (G protein), beta polypeptide 2, also known as GNB2, is a human gene.cite web | title = Entrez Gene: GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2783| accessdate = ]

PBB_Summary
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summary_text = Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR.cite web | title = Entrez Gene: GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2783| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Downes GB, Gautam N |title=The G protein subunit gene families. |journal=Genomics |volume=62 |issue= 3 |pages= 544–52 |year= 2000 |pmid= 10644457 |doi= 10.1006/geno.1999.5992
*cite journal | author=Dawson SJ, White LA |title=Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin. |journal=J. Infect. |volume=24 |issue= 3 |pages= 317–20 |year= 1992 |pmid= 1602151 |doi=
*cite journal | author=Lovett M, Kere J, Hinton LM |title=Direct selection: a method for the isolation of cDNAs encoded by large genomic regions. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 21 |pages= 9628–32 |year= 1991 |pmid= 1946378 |doi=
*cite journal | author=Blatt C, Eversole-Cire P, Cohn VH, "et al." |title=Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 20 |pages= 7642–6 |year= 1988 |pmid= 2902634 |doi=
*cite journal | author=Fong HK, Amatruda TT, Birren BW, Simon MI |title=Distinct forms of the beta subunit of GTP-binding regulatory proteins identified by molecular cloning. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=84 |issue= 11 |pages= 3792–6 |year= 1987 |pmid= 3108879 |doi=
*cite journal | author=Gao B, Gilman AG, Robishaw JD |title=A second form of the beta subunit of signal-transducing G proteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=84 |issue= 17 |pages= 6122–5 |year= 1987 |pmid= 3114742 |doi=
*cite journal | author=Buhl AM, Osawa S, Johnson GL |title=Mitogen-activated protein kinase activation requires two signal inputs from the human anaphylatoxin C5a receptor. |journal=J. Biol. Chem. |volume=270 |issue= 34 |pages= 19828–32 |year= 1995 |pmid= 7649993 |doi=
*cite journal | author=Ray K, Kunsch C, Bonner LM, Robishaw JD |title=Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits. |journal=J. Biol. Chem. |volume=270 |issue= 37 |pages= 21765–71 |year= 1995 |pmid= 7665596 |doi=
*cite journal | author=Pumiglia KM, LeVine H, Haske T, "et al." |title=A direct interaction between G-protein beta gamma subunits and the Raf-1 protein kinase. |journal=J. Biol. Chem. |volume=270 |issue= 24 |pages= 14251–4 |year= 1995 |pmid= 7782277 |doi=
*cite journal | author=Ueda N, Iñiguez-Lluhi JA, Lee E, "et al." |title=G protein beta gamma subunits. Simplified purification and properties of novel isoforms. |journal=J. Biol. Chem. |volume=269 |issue= 6 |pages= 4388–95 |year= 1994 |pmid= 8308009 |doi=
*cite journal | author=Liang JJ, Cockett M, Khawaja XZ |title=Immunohistochemical localization of G protein beta1, beta2, beta3, beta4, beta5, and gamma3 subunits in the adult rat brain. |journal=J. Neurochem. |volume=71 |issue= 1 |pages= 345–55 |year= 1998 |pmid= 9648884 |doi=
*cite journal | author=Glöckner G, Scherer S, Schattevoy R, "et al." |title=Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes. |journal=Genome Res. |volume=8 |issue= 10 |pages= 1060–73 |year= 1998 |pmid= 9799793 |doi=
*cite journal | author=Kleiderlein JJ, Nisson PE, Jessee J, "et al." |title=CCG repeats in cDNAs from human brain. |journal=Hum. Genet. |volume=103 |issue= 6 |pages= 666–73 |year= 1999 |pmid= 9921901 |doi=
*cite journal | author=Asano T, Morishita R, Ueda H, Kato K |title=Selective association of G protein beta(4) with gamma(5) and gamma(12) subunits in bovine tissues. |journal=J. Biol. Chem. |volume=274 |issue= 30 |pages= 21425–9 |year= 1999 |pmid= 10409705 |doi=
*cite journal | author=Suzuki H, Fukunishi Y, Kagawa I, "et al." |title=Protein-protein interaction panel using mouse full-length cDNAs. |journal=Genome Res. |volume=11 |issue= 10 |pages= 1758–65 |year= 2001 |pmid= 11591653 |doi= 10.1101/gr.180101
*cite journal | author=Blake BL, Wing MR, Zhou JY, "et al." |title=G beta association and effector interaction selectivities of the divergent G gamma subunit G gamma(13). |journal=J. Biol. Chem. |volume=276 |issue= 52 |pages= 49267–74 |year= 2002 |pmid= 11675383 |doi= 10.1074/jbc.M106565200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Cuello F, Schulze RA, Heemeyer F, "et al." |title=Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta. |journal=J. Biol. Chem. |volume=278 |issue= 9 |pages= 7220–6 |year= 2003 |pmid= 12486123 |doi= 10.1074/jbc.M210304200
*cite journal | author=Sprague RS, Bowles EA, Olearczyk JJ, "et al." |title=The role of G protein beta subunits in the release of ATP from human erythrocytes. |journal=J. Physiol. Pharmacol. |volume=53 |issue= 4 Pt 1 |pages= 667–74 |year= 2003 |pmid= 12512701 |doi=

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