ADP-specific phosphofructokinase

ADP-specific phosphofructokinase

In enzymology, an ADP-specific phosphofructokinase (EC number|2.7.1.146) is an enzyme that catalyzes the chemical reaction

:ADP + D-fructose 6-phosphate ightleftharpoons AMP + D-fructose 1,6-bisphosphate

Thus, the two substrates of this enzyme are ADP and D-fructose 6-phosphate, whereas its two products are AMP and D-fructose 1,6-bisphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ADP:D-fructose-6-phosphate 1-phosphotransferase. This enzyme is also called ADP-6-phosphofructokinase, ADP-dependent phosphofructokinase.

tructural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|1U2X.

References

*

External links

::"The CAS registry number for this enzyme class is CAS registry|237739-62-7."

Gene Ontology (GO) codes


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