Deacetylvindoline O-acetyltransferase

Deacetylvindoline O-acetyltransferase
17-O-deacetylvindoline O-acetyltransferase
Identifiers
EC number 2.3.1.107
CAS number 100630-41-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a deacetylvindoline O-acetyltransferase (EC 2.3.1.107) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + deacetylvindoline \rightleftharpoons CoA + vindoline

Thus, the two substrates of this enzyme are acetyl-CoA and deacetylvindoline, whereas its two products are CoA and vindoline.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:deacetylvindoline 4-O-acetyltransferase. Other names in common use include deacetylvindoline acetyltransferase, DAT, 17-O-deacetylvindoline-17-O-acetyltransferase, acetylcoenzyme A-deacetylvindoline 4-O-acetyltransferase, acetyl-CoA-17-O-deacetylvindoline 17-O-acetyltransferase, acetylcoenzyme A:deacetylvindoline 4-O-acetyltransferase, acetylcoenzyme A:deacetylvindoline O-acetyltransferase, 17-O-deacetylvindoline O-acetyltransferase, and acetyl-CoA:17-O-deacetylvindoline 17-O-acetyltransferase. This enzyme participates in indole and ipecac alkaloid biosynthesis.

References

  • Fahn W, Gundlach H, Deus-Neumann B and Stockigt J (1985). "Late enzymes of vindoline biosynthesis Acetyl-CoA:17-O-deactylvindoline 17-O-acetyl-transferase". Plant Cell Rep. 4 (6): 333–336. doi:10.1007/BF00269892.