- Decylcitrate synthase
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decylcitrate synthase Identifiers EC number 2.3.3.2 CAS number 9068-72-8 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles Decylcitrate synthase (EC 2.3.3.2) is an enzyme that catalyzes the chemical reaction in enzymology.
- lauroyl-CoA + H2O + oxaloacetate (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA
The 3 substrates of this enzyme are lauroyl-CoA, H2O, and oxaloacetate, whereas its two products are (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate and CoA.
This enzyme belongs to the family of transferases, specifically those acyltransferases that convert acyl groups into alkyl groups on transfer. The systematic name of this enzyme class is dodecanoyl-CoA:oxaloacetate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming). Other names in common use include 2-decylcitrate synthase, (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase, and (CoA-acylating).
References
- Mahlen A, Gatenbeck S (1968). "A metabolic variation in Penicillium spiculisporum Lehman. II Purification and some properties of the enzyme synthesizing (--)-decylcitric acid". Acta. Chem. Scand. 22 (8): 2617–2623. doi:10.3891/acta.chem.scand.22-2617. PMID 5719165.
- Mahlen A (1971). "Properties of 2-decylcitrate synthase from Penicillium spiculisporum Lehman". Eur. J. Biochem. 22 (1): 104–114. doi:10.1111/j.1432-1033.1971.tb01520.x. PMID 5099208.
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