- N-carbamoyl-L-amino-acid hydrolase
-
N-carbamoyl-L-amino-acid hydrolase Identifiers EC number 3.5.1.87 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a N-carbamoyl-L-amino-acid hydrolase (EC 3.5.1.87) is an enzyme that catalyzes the chemical reaction
- N-carbamoyl-L-2-amino acid (a 2-ureido carboxylate) + H2O
L-2-amino acid + NH3 + CO2
Thus, the two substrates of this enzyme are N-carbamoyl-L-2-amino acid and H2O, whereas its 3 products are L-2-amino acid, NH3, and CO2.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-carbamoyl-L-amino acid amidohydrolase.
References
- Ogawa J, Miyake H, Shimizu S (1995). "Purification and characterization of N-carbamoyl-L-amino acid amidohydrolase with broad substrate specificity from Alcaligenes xylosoxidans". Appl. Microbiol. Biotechnol. 43 (6): 1039–43. doi:10.1007/BF00166922. PMID 8590654.
This hydrolase article is a stub. You can help Wikipedia by expanding it. - N-carbamoyl-L-2-amino acid (a 2-ureido carboxylate) + H2O