Dolichyl-phosphatase

dolichyl-phosphatase
Identifiers
EC number	3.1.3.51
CAS number	72994-50-4
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a dolichyl-phosphatase (EC 3.1.3.51) is an enzyme that catalyzes the chemical reaction

dolichyl phosphate + H₂O $\rightleftharpoons$ dolichol + phosphate

Thus, the two substrates of this enzyme are dolichyl phosphate and H₂O, whereas its two products are dolichol and phosphate.

This enzyme belongs to the family of hydrolases, to be specific, those acting on phosphoric monoester bonds. The systematic name of this enzyme class is dolichyl-phosphate phosphohydrolase. Other names in common use include dolichol phosphate phosphatase, dolichol phosphatase, dolichol monophosphatase, dolichyl monophosphate phosphatase, dolichyl phosphate phosphatase, polyisoprenyl phosphate phosphatase, polyprenylphosphate phosphatase, and Dol-P phosphatase. This enzyme participates in n-glycan biosynthesis.

References

• Adrian GS, Keenan RW (1979). "A dolichyl phosphate-cleaving acid phosphatase from Tetrahymena pyriformis". Biochim. Biophys. Acta. 575 (3): 431–8. PMID 229909. 
• Rip JW, Rupar CA, Chaudhary N, Carroll KK (1981). "Localization of a dolichyl phosphate phosphatase in plasma membranes of rat liver". J. Biol. Chem. 256 (4): 1929–34. PMID 6257694. 
• Wedgwood JF, Strominger JL (1980). "Enzymatic activities in cultured human lymphocytes that dephosphorylate dolichyl pyrophosphate and dolichyl phosphate". J. Biol. Chem. 255 (3): 1120–3. PMID 6243292. 

This hydrolase article is a stub. You can help Wikipedia by expanding it.v · Categories: Hydrolase stubs EC 3.1.3 Enzymes of unknown structure Wikimedia Foundation. 2010. Игры ⚽ Нужно решить контрольную? The Newcomers (ballet) Dolichylphosphate-glucose phosphodiesterase Look at other dictionaries: Dolichyl — Dolichyl, related to Dolichol, is used in the names of: Dolichyl beta D glucosyl phosphate, a molecule involved in glycosylation Dolichyl diphosphate polyphosphate phosphotransferase (EC 2.7.4.20) Dolichyl diphosphooligosaccharide protein… …   Wikipedia List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les …   Wikipédia en Français EC 3.1 — Le groupe EC3.1 est un groupe d hydrolases rassemblant les estérases, c est à dire les enzymes catalysant la réaction générale : R O R + H2O ⇌ R OH + R OH où R représente un acide quelconque et R son substrat. En fonction du milieu, l ester… …   Wikipédia en Français Dolichol monophosphate — Preferred IUPAC name [3,7,11,15,19 pentamethylicosa 6,10,14,18 tetraenyl] dihydrogen phosphate …   Wikipedia Dolichyldiphosphatase — Identifiers EC number 3.6.1.43 CAS number 73361 26 9 …   Wikipedia Congenital disorder of glycosylation — Congenital disorders of glycosylation Classification and external resources ICD 10 E77.8 ICD 9 271.8 …   Wikipedia Glycogen phosphorylase — Phosphorylase The crystal structure of the rabit muscle glycogen phosphorylase AMP complex. AMP allosteric site (yellow), phosporylated Ser14 (orange), glycogen binding site (blue), catalytic site (red).[1] …   Wikipedia Glycogen debranching enzyme — Amylo alpha 1, 6 glucosidase, 4 alpha glucanotransferase Identifiers Symbols AGL; GDE External IDs …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”