1-alkyl-2-acetylglycerophosphocholine esterase
- 1-alkyl-2-acetylglycerophosphocholine esterase
In enzymology, a 1-alkyl-2-acetylglycerophosphocholine esterase (EC number|3.1.1.47) is an enzyme that catalyzes the chemical reaction
:1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O 1-alkyl-sn-glycero-3-phosphocholine + acetate
Thus, the two substrates of this enzyme are 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine and H2O, whereas its two products are 1-alkyl-sn-glycero-3-phosphocholine and acetate.
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase. Other names in common use include 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase, and alkylacetyl-GPC:acetylhydrolase. This enzyme participates in ether lipid metabolism.
tructural studies
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1BWP, PDB link|1BWQ, PDB link|1BWR, PDB link|1ES9, PDB link|1FXW, PDB link|1VYH, and PDB link|1WAB.
References
*
External links
::"The CAS registry number for this enzyme class is CAS registry|76901-00-3."
Gene Ontology (GO) codes
Wikimedia Foundation.
2010.
Look at other dictionaries:
Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les … Wikipédia en Français
EC 3.1 — Le groupe EC3.1 est un groupe d hydrolases rassemblant les estérases, c est à dire les enzymes catalysant la réaction générale : R O R + H2O ⇌ R OH + R OH où R représente un acide quelconque et R son substrat. En fonction du milieu, l ester… … Wikipédia en Français
List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… … Wikipedia
PAFAH2 — Platelet activating factor acetylhydrolase 2, 40kDa Identifiers Symbols PAFAH2; FLJ26025; HSD PLA2 External IDs … Wikipedia
PAFAH1B2 — Platelet activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) PDB rendering based on 1fxw … Wikipedia
PAFAH1B3 — Platelet activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) PDB rendering based on 1bwp … Wikipedia
Lipoprotein-associated phospholipase A2 — Phospholipase A2, group VII (platelet activating factor acetylhydrolase, plasma) Rendering based on PDB 3D59 … Wikipedia
