Cancell, also called Protocel, Sheridan's Formula, Jim's Juice, Crocinic Acid, JS–114, JS–101, 126–F, and Entelev, is a formula that has been promoted as a treatment for a wide range of diseases, including cancer. Cancell is available in tablet and liquid form. Originally called Entelev, the formula was developed by biochemist James V. Sheridan. Sheridan sought to target the primarily anaerobic cell respiration of cancer cells (following the theories of Otto Warburg), claiming to lower cell potential leading to the destruction of cancer cells. The Cancell formula was tested by the National Cancer Institute and found to be ineffective against cancer,[1] though Cancell continues to be marketed as a dietary supplement in the U.S.


Formulation and efficacy

The U.S. Food and Drug Administration (FDA) has listed the components as inositol, nitric acid, sodium sulfite, potassium hydroxide, sulfuric acid, and catechol. Precise formulation varies by manufacturer, and may include crocinic acid and various minerals and vitamins.[2]

Researchers at the National Cancer Institute (NCI) tested the constituents of Cancell in animal experiments in 1978 and 1980 and in vitro on human tumors in 1990 and 1991. They concluded that the compounds comprising Cancell could not be taken in doses high enough to kill cancer cells in the body, and that further study was not warranted. No peer-reviewed clinical or animal trials of Cancell have demonstrated any positive effect; claims for Cancell's efficacy are limited to anecdotal reports and testimonials.[1] The American Cancer Society and Memorial Sloan-Kettering Cancer Center recommend against the use of CanCell, as there is no evidence that it is effective in treating any disease, and its proposed method of action is not consistent with modern science.[3][2]

Legal status

Injunction proceedings were instigated by the FDA in June 1987 for manufacturing compliance violations and failure to maintain complaints files. A complaint for permanent injunction was filed February 21, 1989 in the U.S. District Court for the Eastern District of Michigan to enjoin Sheridan and Edward J. Sopcak from distributing CanCell. At a hearing in November 1992, the Court found Sopcak to be in civil contempt and ordered him to comply with the injunction immediately.[4]

Cancell is currently distributed as a dietary supplement under the names Protocel and Entelev, and is not approved by the FDA for use as a cancer treatment or for any other purpose. Since it is marketed as a dietary supplement with no health claims attached, its regulation falls under the Dietary Supplement Health and Education Act of 1994 (DSHEA).


  1. ^ a b "Questions and Answers About Cancell". National Cancer Institute. Retrieved 2008-04-24. 
  2. ^ a b "Cancell". Memorial Sloan-Kettering Cancer Center. Retrieved 2011-02-26. 
  3. ^ "Questionable methods of cancer management: Cancell/Entelev". CA Cancer J Clin 43 (1): 57–62. 1993. doi:10.3322/canjclin.43.1.57. PMID 8422607. 
  4. ^ Segal, Marian. "Court says to cancel the CanCell". FDA Consumer (May 1993: Federal Drug Administration) 27 (4). ISSN 0362-1332. 

External links

 This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".

Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • Cancell — A liquid that has been promoted as a treatment for a wide range of diseases, including cancer. The ingredients thought to be in Cancell have been tested, and none of them has been shown to be effective in treating any form of cancer. Cancell is… …   English dictionary of cancer terms

  • cancell — can|cell Mot Agut Nom masculí …   Diccionari Català-Català

  • cancell — i (L). Latticework …   Dictionary of word roots and combining forms

  • Sonnet 30 — Sonnet|30 When to the sessions of sweet silent thought I summon up remembrance of things past, I sigh the lack of many a thing I sought, And with old woes new wail my dear time s waste: Then can I drown an eye, unused to flow, For precious… …   Wikipedia

  • Wolfmother — Infobox musical artist Name = Wolfmother Img capt = Wolfmother performing at the Beale Street Music Festival on 5 May 2007. From left to right: Andrew Stockdale, Myles Heskett and Chris Ross. Img size = 250 Landscape = Yes Background = group or… …   Wikipedia

  • List of Star Wars planets (T-V) — TaanabIt was at Taanab that Lando Calrissian demonstrated not only his ability to lead but also his knack for devising winning tactics. Lando managed to destroy the attacking space pirates, a feat which later led him to be placed in command of… …   Wikipedia

  • Alternative cancer treatments — describes alternative and complementary treatments for cancer which have not been approved by a governing body (for instance, the United States Food and Drug Administration) as being effective. These treatments are generally not supported by… …   Wikipedia

  • Electric Gardens — infobox music festival music festival name = Electric Gardens location = Kent, England years active= 2006 present dates = August genre = Rock, Alternative rock, Punk rock, Indie rock, Dance website = [ official Website]… …   Wikipedia

  • Elizaveta Ostrogska — Princess Elizaveta Ostrogska (1539 – 1582), olso known as Halszka , was only one child of Prince Ilia Ostrogski and Beata Kościelecka.BiographyBorn in the Ostrog castle 1539 year, soon after her father died. She inherited great fortune which… …   Wikipedia

  • Kaspar Megander — Kaspar Megander, eigentlich Kaspar Grossmann (* 1495 in Zürich; † 18. August 1545 ebenda), war ein reformierter Theologe und Reformator der Schweiz. Inhaltsverzeichnis 1 Leben 2 Werke 3 Literatur …   Deutsch Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”