- Asparagine-tRNA ligase
In
enzymology , an asparagine-tRNA ligase (EC number|6.1.1.22) is anenzyme that catalyzes thechemical reaction :ATP + L-asparagine + tRNAAsn AMP + diphosphate + L-asparaginyl-tRNAAsn
The 3 substrates of this enzyme are ATP,
L-asparagine , andtRNA(Asn) , whereas its 3 products are AMP,diphosphate , andL-asparaginyl-tRNA(Asn) .This enzyme belongs to the family of
ligase s, specifically those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. The systematic name of this enzyme class is L-asparagine:tRNAAsn ligase (AMP-forming). Other names in common use include asparaginyl-tRNA synthetase, asparaginyl-transfer ribonucleate synthetase, asparaginyl transfer RNA synthetase, asparaginyl transfer ribonucleic acid synthetase, asparagyl-transfer RNA synthetase, and asparagine translase. This enzyme participates inalanine and aspartate metabolism andaminoacyl-trna biosynthesis .tructural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1X54, PDB link|1X55, and PDB link|1X56.
References
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External links
::"The
CAS registry number for this enzyme class is CAS registry|37211-76-0."Gene Ontology (GO) codes
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