2-oxoglutarate carboxylase

2-oxoglutarate carboxylase

In enzymology, a 2-oxoglutarate carboxylase (EC number|6.4.1.7) is an enzyme that catalyzes the chemical reaction

:ATP + 2-oxoglutarate + HCO3- ightleftharpoons ADP + phosphate + oxalosuccinate

The 3 substrates of this enzyme are ATP, 2-oxoglutarate, and HCO3-, whereas its 3 products are ADP, phosphate, and oxalosuccinate.

This enzyme belongs to the family of ligases, specifically those forming carbon-carbon bonds. The systematic name of this enzyme class is . Other names in common use include oxalosuccinate synthetase, carboxylating factor for ICDH (incorrect), CFI, and OGC.

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