- Cysteine lyase
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cysteine lyase Identifiers EC number 4.4.1.10 CAS number 9079-86-1 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a cysteine lyase (EC 4.4.1.10) is an enzyme that catalyzes the chemical reaction
- L-cysteine + sulfite L-cysteate + hydrogen sulfide
Thus, the two substrates of this enzyme are L-cysteine and sulfite, whereas its two products are L-cysteate and hydrogen sulfide.
This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is L-cysteine hydrogen-sulfide-lyase (adding sulfite L-cysteate-forming). Other names in common use include cysteine (sulfite) lyase, and L-cysteine hydrogen-sulfide-lyase (adding sulfite). This enzyme participates in cysteine metabolism and taurine and hypotaurine metabolism. It employs one cofactor, pyridoxal phosphate.
References
- Tolosa EA, Chepurnova NK, Khomutov RM, Severin ES (1969). "Reactions catalysed by cysteine lyase from the yolk sac of chicken embryo". Biochim. Biophys. Acta. 171 (2): 369–71. PMID 5813025.
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