HIPK2

HIPK2

Homeodomain interacting protein kinase 2, also known as HIPK2, is a human gene.

PBB_Summary
section_title =
summary_text = HIPK2 is a conserved serine/threonine nuclear kinase that interacts with homeodomain transcription factors. [supplied by OMIM] cite web | title = Entrez Gene: HIPK2 homeodomain interacting protein kinase 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=28996| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Möller A, Schmitz ML |title=Viruses as hijackers of PML nuclear bodies. |journal=Arch. Immunol. Ther. Exp. (Warsz.) |volume=51 |issue= 5 |pages= 295–300 |year= 2004 |pmid= 14626429 |doi=
*cite journal | author=Calzado MA, Renner F, Roscic A, Schmitz ML |title=HIPK2: a versatile switchboard regulating the transcription machinery and cell death. |journal=Cell Cycle |volume=6 |issue= 2 |pages= 139–43 |year= 2007 |pmid= 17245128 |doi=
*cite journal | author=Kim YH, Choi CY, Lee SJ, "et al." |title=Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors. |journal=J. Biol. Chem. |volume=273 |issue= 40 |pages= 25875–9 |year= 1998 |pmid= 9748262 |doi=
*cite journal | author=Kim YH, Choi CY, Kim Y |title=Covalent modification of the homeodomain-interacting protein kinase 2 (HIPK2) by the ubiquitin-like protein SUMO-1. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 22 |pages= 12350–5 |year= 1999 |pmid= 10535925 |doi=
*cite journal | author=Choi CY, Kim YH, Kwon HJ, Kim Y |title=The homeodomain protein NK-3 recruits Groucho and a histone deacetylase complex to repress transcription. |journal=J. Biol. Chem. |volume=274 |issue= 47 |pages= 33194–7 |year= 1999 |pmid= 10559189 |doi=
*cite journal | author=Li X, Wang Y, Debatin KM, Hug H |title=The serine/threonine kinase HIPK2 interacts with TRADD, but not with CD95 or TNF-R1 in 293T cells. |journal=Biochem. Biophys. Res. Commun. |volume=277 |issue= 2 |pages= 513–7 |year= 2000 |pmid= 11032752 |doi= 10.1006/bbrc.2000.3700
*cite journal | author=Hofmann TG, Mincheva A, Lichter P, "et al." |title=Human homeodomain-interacting protein kinase-2 (HIPK2) is a member of the DYRK family of protein kinases and maps to chromosome 7q32-q34. |journal=Biochimie |volume=82 |issue= 12 |pages= 1123–7 |year= 2001 |pmid= 11120354 |doi=
*cite journal | author=Wang Y, Hofmann TG, Runkel L, "et al." |title=Isolation and characterization of cDNAs for the protein kinase HIPK2. |journal=Biochim. Biophys. Acta |volume=1518 |issue= 1-2 |pages= 168–72 |year= 2001 |pmid= 11267674 |doi=
*cite journal | author=Missero C, Pirro MT, Simeone S, "et al." |title=The DNA glycosylase T:G mismatch-specific thymine DNA glycosylase represses thyroid transcription factor-1-activated transcription. |journal=J. Biol. Chem. |volume=276 |issue= 36 |pages= 33569–75 |year= 2001 |pmid= 11438542 |doi= 10.1074/jbc.M104963200
*cite journal | author=Wang Y, Debatin KM, Hug H |title=HIPK2 overexpression leads to stabilization of p53 protein and increased p53 transcriptional activity by decreasing Mdm2 protein levels. |journal=BMC Mol. Biol. |volume=2 |issue= |pages= 8 |year= 2003 |pmid= 11532197 |doi=
*cite journal | author=Pierantoni GM, Fedele M, Pentimalli F, "et al." |title=High mobility group I (Y) proteins bind HIPK2, a serine-threonine kinase protein which inhibits cell growth. |journal=Oncogene |volume=20 |issue= 43 |pages= 6132–41 |year= 2001 |pmid= 11593421 |doi= 10.1038/sj.onc.1204635
*cite journal | author=Hofmann TG, Möller A, Sirma H, "et al." |title=Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2. |journal=Nat. Cell Biol. |volume=4 |issue= 1 |pages= 1–10 |year= 2002 |pmid= 11740489 |doi= 10.1038/ncb715
*cite journal | author=D'Orazi G, Cecchinelli B, Bruno T, "et al." |title=Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis. |journal=Nat. Cell Biol. |volume=4 |issue= 1 |pages= 11–9 |year= 2002 |pmid= 11780126 |doi= 10.1038/ncb714
*cite journal | author=Pierantoni GM, Bulfone A, Pentimalli F, "et al." |title=The homeodomain-interacting protein kinase 2 gene is expressed late in embryogenesis and preferentially in retina, muscle, and neural tissues. |journal=Biochem. Biophys. Res. Commun. |volume=290 |issue= 3 |pages= 942–7 |year= 2002 |pmid= 11798164 |doi= 10.1006/bbrc.2001.6310
*cite journal | author=Kim EJ, Park JS, Um SJ |title=Identification and characterization of HIPK2 interacting with p73 and modulating functions of the p53 family in vivo. |journal=J. Biol. Chem. |volume=277 |issue= 35 |pages= 32020–8 |year= 2002 |pmid= 11925430 |doi= 10.1074/jbc.M200153200
*cite journal | author=Wang Y, Marion Schneider E, Li X, "et al." |title=HIPK2 associates with RanBPM. |journal=Biochem. Biophys. Res. Commun. |volume=297 |issue= 1 |pages= 148–53 |year= 2002 |pmid= 12220523 |doi=
*cite journal | author=Scherer SW, Cheung J, MacDonald JR, "et al." |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423
*cite journal | author=Tomasini R, Samir AA, Carrier A, "et al." |title=TP53INP1s and homeodomain-interacting protein kinase-2 (HIPK2) are partners in regulating p53 activity. |journal=J. Biol. Chem. |volume=278 |issue= 39 |pages= 37722–9 |year= 2003 |pmid= 12851404 |doi= 10.1074/jbc.M301979200
*cite journal | author=Hillier LW, Fulton RS, Fulton LA, "et al." |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782
*cite journal | author=Harada J, Kokura K, Kanei-Ishii C, "et al." |title=Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein-induced transcriptional activation. |journal=J. Biol. Chem. |volume=278 |issue= 40 |pages= 38998–9005 |year= 2003 |pmid= 12874272 |doi= 10.1074/jbc.M307112200

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