Pyruvate dehydrogenase (cytochrome)
- Pyruvate dehydrogenase (cytochrome)
In enzymology, a pyruvate dehydrogenase (cytochrome) (EC number|1.2.2.2) is an enzyme that catalyzes the chemical reaction
:pyruvate + ferricytochrome b1 + H2O acetate + CO2 + ferrocytochrome b1
The 3 substrates of this enzyme are pyruvate, ferricytochrome b1, and H2O, whereas its 3 products are acetate, CO2, and ferrocytochrome b1.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with a cytochrome as acceptor. The systematic name of this enzyme class is pyruvate:ferricytochrome-b1 oxidoreductase. Other names in common use include pyruvate dehydrogenase, pyruvic dehydrogenase, pyruvic (cytochrome b1) dehydrogenase, pyruvate:ubiquinone-8-oxidoreductase, and pyruvate oxidase (ambiguous). This enzyme participates in pyruvate metabolism. It has 2 cofactors: FAD, and Thiamin diphosphate.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|9079-84-9."
Gene Ontology (GO) codes
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