D-lactate dehydrogenase (cytochrome c-553)

D-lactate dehydrogenase (cytochrome c-553)
Identifiers
EC number	1.1.2.5
CAS number	37250-79-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a D-lactate dehydrogenase (cytochrome c-553) (EC 1.1.2.5) is an enzyme that catalyzes the chemical reaction

(R)-lactate + 2 ferricytochrome c-553 $\rightleftharpoons$ pyruvate + 2 ferrocytochrome c-553

Thus, the two substrates of this enzyme are (R)-lactate and ferricytochrome c-553, whereas its two products are pyruvate and ferrocytochrome c-553.

This enzyme belongs to the family of oxidoreductases, to be specific those acting on the CH-OH group of donor with a cytochrome as acceptor. The systematic name of this enzyme class is (R)-lactate:ferricytochrome-c-553 2-oxidoreductase. This enzyme participates in pyruvate metabolism.

References

• Ogata M, Arihara K and Yagi T (Tokyo). "D-Lactate dehydrogenase of Desulfovibrio vulgaris". J. Biochem.: 1423–1431.