- Glycerate dehydrogenase
In
enzymology , a glycerate dehydrogenase (EC number|1.1.1.29) is anenzyme that catalyzes thechemical reaction :(R)-glycerate + NAD+ hydroxypyruvate + NADH + H+
Thus, the two substrates of this enzyme are
(R)-glycerate and NAD+, whereas its 3 products arehydroxypyruvate , NADH, and H+.This enzyme belongs to the family of
oxidoreductase s, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-glycerate:NAD+ oxidoreductase. Other names in common use include D-glycerate dehydrogenase, and hydroxypyruvate reductase. This enzyme participates inglycine, serine and threonine metabolism andglyoxylate and dicarboxylate metabolism .tructural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|1GDH.
References
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*External links
::"The
CAS registry number for this enzyme class is CAS registry|9028-37-9."Gene Ontology (GO) codes
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