Glucose 1-dehydrogenase (NAD+)

Glucose 1-dehydrogenase (NAD+)

In enzymology, a glucose 1-dehydrogenase (NAD+) (EC number|1.1.1.118) is an enzyme that catalyzes the chemical reaction

:D-glucose + NAD+ ightleftharpoons D-glucono-1,5-lactone + NADH + H+

Thus, the two substrates of this enzyme are D-glucose and NAD+, whereas its 3 products are D-glucono-1,5-lactone, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-glucose:NAD+ 1-oxidoreductase. Other names in common use include D-glucose:NAD+ oxidoreductase, D-aldohexose dehydrogenase, and glucose 1-dehydrogenase (NAD+).

tructural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|2DTD, PDB link|2DTE, and PDB link|2DTX.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|37250-49-0."

Gene Ontology (GO) codes


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