Pancrelipase

Pancrelipase

Clinical data
AHFS/Drugs.com	monograph
MedlinePlus	a604035
Pregnancy cat.	?
Legal status	?
Routes	Oral
Identifiers
CAS number	53608-75-6 Y
ATC code	A09AA02
DrugBank	DB00085
UNII	FQ3DRG0N5K Y
Chemical data
Formula	C5850H8902N1606O1739S49
Mol. mass	131 kDa
N(what is this?)  (verify)

Pancrelipase is a form of enzyme therapy for the treatment of various digestive disorders, primarily exocrine pancreatic insufficiency. It is a mixture of three digestive enzymes, amylase, trypsin, and lipase, which are normally produced by the pancreas. Pancrelipase is a form of pancreatin having a elevated content of lipase.

Use

Pancrelipase is used by patients suffering from cystic fibrosis, chronic pancreatitis and after pancreatectomy.

Brand names for Pancrelipase include Creon, Pancrease, Ultrase, Mezym and Ozym.

Creon

Creon is a Pancrelipase manufactured and produce by Abbott Laboratories. Its available in different packaging ie Creon 5, 10 or 20.

Creon 10,000 mini-microspeheres (delayed release capsules) is available in China, Singapore, Malaysia and Thailand with enzyme contains lipase 10,000 u, amylase 8,000 u, protease 600 u.^[1]

Its main indication is for patients with pancretic exocrine insufficiency ie, cystic fibrosis, chronic pancreatitis, pancreatectomy, pancreatic cancer and gastrotectomy.

References

1. ^ "Creon 10000: Drug information, CME and news". MIMS.com. http://www.mims.com/Creon%2010000.html. Retrieved 2011-11-06. 

External links

• Pancrelipase

This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it.v · Categories: Enzymes Gastrointestinal system drug stubs Wikimedia Foundation. 2010. Игры ⚽ Нужна курсовая? Psychological novel Zymase Look at other dictionaries: pancrelipase — A concentrate of pancreatic enzymes standardized for lipase content; a lipolytic used for substitution therapy. SYN: lipancreatin. * * * pan·cre·li·pase (pan″kre liґpās) [USP] a standardized preparation of hog pancreas, containing… …   Medical dictionary Exocrine pancreatic insufficiency — Infobox Disease Name = PAGENAME Caption = DiseasesDB = ICD10 = ICD9 = ICD9|577.8 ICDO = OMIM = MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = D010188 Exocrine pancreatic insufficiency (EPI) is the inability to properly digest food due to …   Wikipedia Diastase — A diastase (pronounced /ˈdaɪəsteɪz/; from Greek διαστασις, separation ) is any one of a group of enzymes which catalyses the breakdown of starch into maltose. Alpha amylase degrades starch to a mixture of the disaccharide maltose, the… …   Wikipedia Zymase — is an enzyme complex ( mixture ) that catalyzes glycolysis, the fermentation of sugar into ethanol and carbon dioxide. As the conversion takes place, the reaction will gradually slow down. They occur naturally in yeasts. See alcohol dehydrogenase …   Wikipedia Pancreatin — is a mixture of several digestive enzymes produced by the exocrine cells of the pancreas. It is composed of amylase, lipase and protease. This mixture is used to treat conditions in which pancreatic secretions are deficient, such as pancreatitis… …   Wikipedia lipancreatin — SYN: pancrelipase …   Medical dictionary Cotazym — Cot·a·zym (kotґə zīm) trademark for preparations of pancrelipase …   Medical dictionary Creon — Cre·on (kreґon) trademark for a preparation of pancrelipase …   Medical dictionary Ilozyme — Il·o·zyme (ilґo zīm) trademark for a preparation of pancrelipase …   Medical dictionary Kutrase — Ku·trase (kuґtrās) trademark for a preparation of pancrelipase …   Medical dictionary 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”