U6 spliceosomal RNA

U6 spliceosomal RNA

U6 snRNA is a non-coding RNA that is a component of the spliceosome which is involved in splicing pre-mRNA. The putative secondary structure consensus base pairing is confined to a short 5' stem-loop, but U6 snRNA is thought to form extensive base-pair interactions with U4 snRNA. [cite journal | last = Orum | first = H | coauthors = Nielsen H, Engberg J | year = 1991 | title = Spliceosomal small nuclear RNAs of Tetrahymena thermophila and some possible snRNA-snRNA base-pairing interactions | journal = J Mol Biol | volume = 222 | pages = 219–232 | pmid = 1960724 | doi = 10.1016/0022-2836(91)90208-N] There appear to be many copies of U6 derived pseudogenes or repeats in vertebrate genomes.

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