Dysfunctional uterine bleeding

Dysfunctional uterine bleeding

DiseaseDisorder infobox
Name = Dysfunctional uterine bleeding
ICD10 =
ICD9 = ICD9|626.8

Dysfunctional Uterine Bleeding (DUB) is the most common cause of functional abnormal uterine bleeding, which is abnormal genital tract bleeding based in the uterus and found in the absence of demonstrable organic pathology.Diagnosis must be made by exclusion, since organic pathology must first be ruled out.It can be classified as "ovulatory" or "anovulatory", depending on whether ovulation is occurring or not.

Ovulatory

Ovulatory DUB happens with the involvement of ovulation, and may represent a possible endocrine dysfunction, resulting in menorrhagia or metrorrhagia.Mid-cycle bleeding may indicate a transient estrogen decline, while late-cycle bleeding may indicate progesterone deficiency.

Anovulatory

Anovulatory cycle DUB happens without the involvement of ovulation.The etiology can be psychological stress, weight (obesity, anorexia, or a rapid change), exercise, endocrinopathy, neoplasm, drugs, or it may be otherwise idiopathic.

Assessment of anovulatory DUB should always start with a good medical history and physical examination.Laboratory assessment of hemoglobin, luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin, T4, thyroid stimulating hormone (TSH), pregnancy (by βhCG), and androgen profile should also happen.More extensive testing might include an ultrasound and endometrial sampling.

Management

Management of dysfunctional uterine bleeding predominantly consists of reassurance, though mid-cycle estrogen and late-cycle progestin can be used for mid- and late-cycle bleeding respectively.Also, non-specific hormonal therapy such as combined estrogen and progestin can be given.

The goal of therapy should be to arrest bleeding, replace lost iron to avoid anemia, and prevent future bleeding.

Resources

* [http://www.merck.com/mrkshared/mmanual/home.jsp Merck Manual] : [http://www.merck.com/mrkshared/mmanual/section18/chapter235/235e.jsp Abnormal Uterine Bleeding]


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • dysfunctional uterine bleeding — n abnormal uterine bleeding that is not associated with a physical lesion (as a tumor), inflammation, or pregnancy abbr. DUB * * * (DUB) bleeding from the uterus when no organic uterine lesions are present …   Medical dictionary

  • dysfunctional uterine bleeding — see menorrhagia …   Medical dictionary

  • dysfunctional uterine bleeding — see menorrhagia …   The new mediacal dictionary

  • uterine bleeding — Abnormal bleeding from the uterus not related to menstruation. Most common in the first few years after menarche and as menopause approaches, it is thought to occur when malfunctioning ovaries reduce blood estrogen levels. A malfunctioning… …   Universalium

  • Uterine prolapse — Female genital prolapse Classification and external resources ICD 10 N81.4 ICD 9 618.1 …   Wikipedia

  • bleeding — 1. Losing blood as a result of the rupture or severance of blood vessel s. 2. Phlebotomy; the letting of blood. dysfunctional uterine b. uterine b. due to a benign endocrine abnormality rather than to any or …   Medical dictionary

  • Uterine rupture — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 13642 ICD10 = ICD10|O|71|0|o|60 ICD10|O|71|1|o|60 ICD9 = ICD9|665.1 ICDO = OMIM = MedlinePlus = eMedicineSubj = med eMedicineTopic = 3746 MeshID = D014597Uterine rupture is a potentially… …   Wikipedia

  • Vaginal bleeding — DiseaseDisorder infobox Name = Vaginal bleeding ICD10 = N92 N93 ICD9 = Vaginal bleeding refers to bleeding in females that is either a physiologic response during the non conceptional menstrual cycle or caused by hormonal or organic problems of… …   Wikipedia

  • breakthrough bleeding — break·through bleeding .brāk .thrü n an abnormal flow of blood from the uterus that occurs between menstrual periods esp. due to irregular sloughing of the endometrium in women on contraceptive hormones * * * a light type of dysfunctional uterine …   Medical dictionary

  • DUB — • dysfunctional uterine bleeding …   Dictionary of medical acronyms & abbreviations

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”