CAMP receptor protein

CAMP receptor protein

Protein
Name=PAGENAME


caption=Structure of the "E. coli" Cyclic AMP Receptor Protein.
Symbol=CRP
AltSymbols=CAP
EntrezGene=289905
RefSeq=NP_289905
UniProt=P0ACK0
PDB=1I5Z

cAMP receptor protein (in short CRP, also known as catabolite gene activator protein (in short CAP)) is a regulatory protein in bacteria. This protein binds cAMP, which causes a conformational change that allows the protein to bind tightly to a specific DNA sequence in the promoters of the genes it controls. [cite journal |author=Harman JG |title=Allosteric regulation of the cAMP receptor protein |journal=Biochim. Biophys. Acta |volume=1547 |issue=1 |pages=1–17 |year=2001 |pmid=11343786] The genes regulated by this protein are mostly involved in energy metabolism, such as galactose, citrate, or the PEP group translocation system. [cite journal |author=Weickert MJ, Adhya S |title=The galactose regulon of Escherichia coli |journal=Mol. Microbiol. |volume=10 |issue=2 |pages=245–51 |year=1993 |pmid=7934815 |doi=10.1111/j.1365-2958.1993.tb01950.x] [cite journal |author=Bott M |title=Anaerobic citrate metabolism and its regulation in enterobacteria |journal=Arch. Microbiol. |volume=167 |issue=2-3 |pages=78–88 |year=1997 |pmid=9133329 |doi=10.1007/s002030050419]

References

External links

[http://www.mun.ca/biochem/courses/4103/topics/CRP.html crystal structure of CRP and binding site properties]


Wikimedia Foundation. 2010.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • cAMP receptor protein — Structure of the E. coli Cyclic AMP Receptor Protein. Identifiers Symbol CRP Alt. symbols CAP …   Wikipedia

  • cAMP receptor protein — catabolite activator p …   Medical dictionary

  • Protein tyrosine phosphatase — Protein tyrosine phosphatases (PTPs) are a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins. Protein tyrosine (pTyr) phosphorylation is a common post translational modification that can create novel… …   Wikipedia

  • Protein kinase D1 — Protein kinase D1, also known as PRKD1, is a human gene.cite web | title = Entrez Gene: PRKD1 protein kinase D1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=5587| accessdate = ] PBB Summary section title …   Wikipedia

  • Protein kinase A — In cell biology, Protein kinase A (PKA) refers to a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA is also known as cAMP dependent protein kinase (EC 2.7.11.11). Protein kinase A has several functions… …   Wikipedia

  • Receptor (biochemistry) — For other uses, see Receptor (disambiguation). In biochemistry, a receptor is a molecule found on the surface of a cell, which receives specific chemical signals from neighbouring cells or the wider environment within an organism. These signals… …   Wikipedia

  • CAMP dependent pathway — In the field of molecular biology, the cAMP dependent pathway, also known as the adenylyl cyclase pathway, is a G protein coupled receptor triggered signaling cascade used in cell communication.cite book | author = Bruce Alberts, Alexander… …   Wikipedia

  • Protein — A large molecule composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein. Proteins are required for the structure, function, and regulation of the body s… …   Medical dictionary

  • Protein kinase — A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation). This class of protein may further be separated into subsets as in the case of protein kinase C PKC alpha, PKC beta,… …   Wikipedia

  • FSH-receptor — Follicle stimulating hormone receptor PDB rendering based on 1xwd …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”