Cyclin-dependent kinase complex
- Cyclin-dependent kinase complex
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A cyclin-dependent kinase complex (abbreviated cdkc, also called cyclin-CDK) is a protein complex formed by the association of cyclin with cyclin-dependent kinase. These complexes are able to phosphorylate other compounds under consumption of ATP, and are thereby involved in the regulation of the cell cycle. Depending on the type of cyclin attached to CDK, it has a different function. These serve as markers in each phase which are integral for the correct sequence of events, as well as facilitating the transition to the next phase.
Classes
There are three classes of cdkc depending on the phase of the cell cycle.
See also
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cyclin-dependent kinase — Family of kinases including cdc28, cdc2 and p34cdc2 that are only active when they form a complex with cyclins. The complex is maturation promoting factor (MPF) and its activity is necessary for cells to leave G2 and enter mitosis. Catalytic… … Dictionary of molecular biology
Expression of cyclins through the cell cycle.
