Diabetic foot

Diabetic foot

A diabetic foot is a foot that exhibits any pathology that results directly from diabetes mellitus or any long-term (or "chronic") complication of diabetes mellitus.[1] Presence of several characteristic diabetic foot pathologies is called diabetic foot syndrome. These are thus umbrella terms.

The most serious foot complications in diabetes are:[2]

  • Diabetic foot ulceration. It occurs in 15% of all patients with diabetes and precedes 84% of all lower leg amputations.[3]
  • Diabetic foot infections
  • Neuropathic osteoarthropathy of the foot

Prevention

"Of all methods proposed to prevent diabetic foot ulcers, only foot temperature-guided avoidance therapy was found beneficial in RCTs" according to a meta-analysis.[4]

References

  1. ^ [1] [2] Boulton in Diabetes, 30;36 2002
  2. ^ Frykberg RG, Armstrong DG, Giurini J, et al. (2000). "Diabetic foot disorders: a clinical practice guideline. American College of Foot and Ankle Surgeons". J Foot Ankle Surg 39 (5 Suppl): S1–60. PMID 11280471. http://ukpmc.ac.uk/abstract/MED/11280471/reload=0;jsessionid=C38C571D5D1CB95F188AC5E80A9D6B05.jvm1. 
  3. ^ Brem Harold, Tomic-Canic Marjana (2007). "Cellular and Molecular basis of wound healing in diabetes". JCI 117 (5): 1219–1222. doi:10.1172/JCI32169. PMC 1857239. PMID 17476353. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1857239. 
  4. ^ Arad Y, Fonseca V, Peters A, Vinik A (2011). "Beyond the Monofilament for the Insensate Diabetic Foot: A systematic review of randomized trials to prevent the occurrence of plantar foot ulcers in patients with diabetes". Diabetes Care 34 (4): 1041–6. doi:10.2337/dc10-1666. PMC 3064020. PMID 21447666. http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21447666. 
v · d · eDiabetes (E10–E14, 250)
Types of diabetes
Prediabetes (Impaired fasting glucose, Impaired glucose tolerance)
Type 1 · Type 1.5 · Type 2 · MODY · NDM (Transient, Permanent)
Blood tests
Blood sugar · Glycosylated hemoglobin · Glucose tolerance test · Fructosamine
Diabetes management
Complications/prognosis
Lines of research

M: END

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