- Hydrazide
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P-toluenesulfonylhydrazide (1) and 1,3,5-triisopropylbenzenesulfonylhydrazide (2)Hydrazides in organic chemistry are a class of organic compounds sharing a common functional group characterized by a nitrogen to nitrogen covalent bond with 4 substituents with at least one of them being an acyl group.[1] The general structure for an hydrazide is (R1=O)R2-N-N-R3R4. A related class of compounds called hydrazines do not carry an acyl group.[2] Important members of this class are sulfonylhydrazides such as p-toluenesulfonylhydrazide which are useful reagents in organic chemistry such as in the Shapiro reaction. This reagent can be prepared by reaction of tosyl chloride with hydrazine.[3]
References
- ^ IUPAC, Compendium of Chemical Terminology, 2nd ed. (the "Gold Book") (1997). Online corrected version: (2006–) "Hydrazides".
- ^ IUPAC, Compendium of Chemical Terminology, 2nd ed. (the "Gold Book") (1997). Online corrected version: (2006–) "Hydrazines".
- ^ Lester Friedman; Robert L. Litle; Walter R. Reichle (1960), "p-toluenesulfonylhydrazide", Org. Synth. 40: 93, http://www.orgsyn.org/orgsyn/orgsyn/prepContent.asp?prep=cv5p1055; Coll. Vol. 5: 1055
Hydrazines 4-PTSC • Acylhydrazine • ADH • Adjudin • Agaritine • Benmoxin • Cadralazine • Carbazide • Carbazone • Carbidopa • Carbohydrazide • Daminozide • Dihydralazine • DNPH • Endralazine • Gyromitrin • HBT • Hydralazine • Hydrazide • Hydrazine • Hydrazone • IDH • Iproclozide • Iproniazid • Isocarboxazid • Isoniazid • Mebanazine • Metfendrazine • MMH • Nialamide • Octamoxin • PEH • Phenelzine • Pheniprazine • Phenoxypropazine • Phenylhydrazine • Pimagedine • Pivalylbenzhydrazine • Procarbazine • Safrazine • SDH • Semicarbazide • Semicarbazone • SDMH • Tetrafluorohydrazine • Thiosemicarbazide • Thiosemicarbazone • UDMHCategories:- Functional groups
- Hydrazides
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