NS-398

NS-398: NS-398^[1]

IUPAC name

N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide

Identifiers

CAS number 123653-11-2

PubChem 4553

Jmol-3D images Image 1

SMILES

CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2CCCCC2

Properties

Molecular formula C₁₃H₁₈N₂O₅S

Molar mass 314.36 g mol⁻¹

Appearance Off-white solid

Solubility in water Insoluble

Solubility in DMSO 5 mg/mL

Hazards

S-phrases S22 S24/25

Y (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)

Infobox references

NS-398 is a COX-2 inhibitor used in the study of the function of cyclooxygenases.^[2]

See also

Celecoxib

JTE-522

References

^ NS-398 at Sigma-Aldrich

^ Wei Shen, Yong Li, Ying Tang, James Cummins and Johnny Huard (2005). "NS-398, a Cyclooxygenase-2-Specific Inhibitor, Delays Skeletal Muscle Healing by Decreasing Regeneration and Promoting Fibrosis". American Journal of Pathology 167 (4): 1105–1117. PMC 1603662. PMID 16192645. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1603662.

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Academic Dictionaries and Encyclopedias

NS-398^[1]

IUPAC name N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide
Identifiers
CAS number	123653-11-2
PubChem	4553
Jmol-3D images	Image 1
SMILES CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2CCCCC2
Properties
Molecular formula	C₁₃H₁₈N₂O₅S
Molar mass	314.36 g mol⁻¹
Appearance	Off-white solid
Solubility in water	Insoluble
Solubility in DMSO	5 mg/mL
Hazards
S-phrases	S22 S24/25
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references