- NINL
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Ninein-like Identifiers Symbols NINL; FLJ11792; KIAA0980; NLP; dJ691N24.1 External IDs OMIM: 609580 MGI: 1925427 HomoloGene: 57024 GeneCards: NINL Gene Gene Ontology Molecular function • calcium ion binding Cellular component • cytoplasm
• microtubule organizing center
• cytosol
• cytoskeleton
• microtubuleBiological process • G2/M transition of mitotic cell cycle
• mitotic cell cycleSources: Amigo / QuickGO RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 22981 78177 Ensembl ENSG00000101004 ENSMUSG00000068115 UniProt Q9Y2I6 Q6ZQ12 RefSeq (mRNA) NM_025176 NM_207204.2 RefSeq (protein) NP_079452 NP_997087.2 Location (UCSC) Chr 20:
25.43 – 25.57 MbChr 2:
150.76 – 150.87 MbPubMed search [1] [2] Ninein-like protein is a protein that in humans is encoded by the NINL gene.[1][2] It is part of the centrosome[3].
References
- ^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jul 1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.
- ^ "Entrez Gene: RP4-691N24.1 KIAA0980 protein". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22981.
- ^ Casenghi, Martina (2003). Functional characterization of the novel centrosomal protein Nlp (ninein-like protein) (Ph.D thesis). http://edoc.ub.uni-muenchen.de/1962/1/Casenghi_Martina.pdf.
Further reading
- Wang Y, Zhan Q (2007). "Cell cycle-dependent expression of centrosomal ninein-like protein in human cells is regulated by the anaphase-promoting complex.". J. Biol. Chem. 282 (24): 17712–9. doi:10.1074/jbc.M701350200. PMID 17403670.
- Casenghi M, Barr FA, Nigg EA (2005). "Phosphorylation of Nlp by Plk1 negatively regulates its dynein-dynactin-dependent targeting to the centrosome.". J. Cell. Sci. 118 (Pt 21): 5101–8. doi:10.1242/jcs.02622. PMID 16254247.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Casenghi M, Meraldi P, Weinhart U, et al. (2003). "Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation.". Dev. Cell 5 (1): 113–25. doi:10.1016/S1534-5807(03)00193-X. PMID 12852856.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20.". Nature 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
The centrosome and its components Centrioles Pericentriolar material other proteins Categories:- Human proteins
- Chromosome 20 gene stubs
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