Methyldesorphine

Methyldesorphine

Systematic (IUPAC) name
(5α)-6,17-dimethyl- 6,7-didehydro- 4,5-epoxymorphinan- 3-ol
Clinical data
Pregnancy cat.	?
Legal status	Schedule I (US)
Identifiers
CAS number	16008-36-9 Y
ATC code	None
PubChem	CID 5362518
UNII	Y460N7W76B N
Synonyms	3-Hydroxy-6,N-dimethyl- 4,5-epoxymorphin-6-en
Chemical data
Formula	C18H21NO2
Mol. mass	283.36 g/mol
SMILES	eMolecules & PubChem
N(what is this?)  (verify)

Methyldesorphine is an opioid analgesic. First synthesized in Germany in 1940 and patented in the USA in 1952,^[1] it has a high potential for abuse as with any potent opioid agonist, and is sometimes found along with desomorphine as a component of the home-made opioid mixture known as "Krokodil" used in Russia and the neighboring former Soviet republics.^[2] It is approximately 15 times more potent than morphine as an analgesic^[3][4] but if the 6-7 bond is saturated, the β isomer is some 50 times more potent than morphine.

See also

• 6-Methylenedihydrodesoxymorphine

References

1. ^ US patent 2694068, George B. Payne et al, "Δ6-DESOXYMORPHINE COMPOUNDS AND PROCESS OF PRODUCING THE SAME", published 1952-08-05, issued 1954-09-11 
2. ^ Savchuk, S. A.; Barsegyan, S. S.; Barsegyan, I. B.; Kolesov, G. M. (2008). "Chromatographic study of expert and biological samples containing desomorphine". Journal of Analytical Chemistry 63 (4): 361-370. doi:10.1007/s10809-008-4009-5.  edit
3. ^ Casy AF, Parfitt RY. Opioid analgesics, chemistry and receptors. 1986, Plenum Press, New York. pp 37-38. ISBN 0306421305
4. ^ Lenz GR, Evans SM, Walters DE, Hopfinger AJ. Opiates (1986). p63. Academic Press. ISBN 978-0124438309

This analgesic-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Morphinans Phenols Ethers Mu-opioid agonists Semisynthetic opioids Analgesic stubs Wikimedia Foundation. 2010. Игры ⚽ Нужен реферат? Methylcyclopentane Azure A Look at other dictionaries: methyldesorphine — noun An opiate analgesic with high potential for abuse …   Wiktionary Opioid — Endogenous opioid peptides Skeletal molecular images Adrenorphin Amidorphin Casomorphin …   Wikipedia Morphine — This article is about the drug. For other meanings, see Morphine (disambiguation). Morphia redirects here. For other uses, see Morphia (disambiguation). Not to be confused with Morphinae, Morphea, or Morpholine. Morphine …   Wikipedia Opiate — For other uses see Opiate (disambiguation), or for the class of drugs see Opioid. Harvesting the poppy pod. In medicine, the term opiate describes any of the narcotic opioid alkaloids found as natural products in the opium poppy plant …   Wikipedia Phencyclidine — Systematic (IUPAC) name …   Wikipedia Loperamide — Imodium redirects here. For the song by Nirvana, see Breed (song). Loperamide Systematic (IUPAC) name …   Wikipedia Pethidine — Systematic (IUPAC) name …   Wikipedia Opioid receptor — Opioid receptors are a group of G protein coupled receptors with opioids as ligands.[1][2][3] The endogenous opioids are dynorphins, enkephalins, endorphins, endomorphins and nociceptin. The opioid receptors are 40% identical to somatostatin… …   Wikipedia Oxymorphone — Systematic (IUPAC) name 4,5α epoxy 3,14 dihydroxy 17 methylmorphinan 6 one Clinical data Trade names …   Wikipedia Sufentanil — Systematic (IUPAC) name N [4 (methoxymethyl) …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”