dnaG

DNA primase
Identifiers
Symbol	dnaG
Alt. symbols	dnaP
Entrez	947570
UniProt	P0ABS5
Other data
EC number	2.7.7.7

DnaG is a bacterial primase which synthesizes short RNA oligonucleotides during DNA replication. These RNA oligonucleotides serve as primers for DNA synthesis by bacterial DNA polymerase Pol III. On one of the two parental strands, called the lagging strand, the primase makes a primer every few kilobases. These primers serve a substrates for synthesis of Okazaki fragments.

DnaG associates with bacterial replicative helicase DnaB to perform its primase activity. About three DnaG primase proteins associate with each DnaB helicase.

External links

• MeSH dnaG+protein,+E+coli
• MeSH DnaG+(Primase)

Replication

Prokaryotic (elongation)	DNA polymerase III holoenzyme (dnaC, dnaE, dnaH, dnaN, dnaQ, dnaT, dnaX) · Replisome · DNA ligase · DNA clamp · Topoisomerase (DNA gyrase) Prokaryotic DNA polymerase: DNA polymerase I (Klenow fragment)
Eukaryotic (synthesis in S phase)	Replication factor C (RFC1) · Flap endonuclease (FEN1) · Topoisomerase · Replication protein A (RPA1) Eukaryotic DNA polymerase: delta (POLD1, POLD2, POLD3, POLD4) DNA clamp (PCNA)
Both	Movement: Processivity · DNA ligase

Termination

Telomere: Telomerase (TERT, TERC, DKC1)

see also DNA replication and repair-deficiency disorder
B bsyn: dna (repl, cycl, reco, repr) · tscr (fact, tcrg, nucl, rnat, rept, ptts) · tltn (risu, pttl, nexn) · dnab, rnab/runp · stru (domn, 1°, 2°, 3°, 4°)