POLD1

POLD1

Polymerase (DNA directed), delta 1, catalytic subunit 125kDa, also known as POLD1, is a human gene.cite web | title = Entrez Gene: POLD1 polymerase (DNA directed), delta 1, catalytic subunit 125kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5424| accessdate = ]

PBB_Summary
section_title =
summary_text =

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kemper RR, Ahn ER, Zhang P, "et al." |title=Human DNA polymerase delta gene maps to region 19q13.3-q13.4 by in situ hybridization. |journal=Genomics |volume=14 |issue= 1 |pages= 205–6 |year= 1992 |pmid= 1427831 |doi=
*cite journal | author=Yang CL, Chang LS, Zhang P, "et al." |title=Molecular cloning of the cDNA for the catalytic subunit of human DNA polymerase delta. |journal=Nucleic Acids Res. |volume=20 |issue= 4 |pages= 735–45 |year= 1992 |pmid= 1542570 |doi=
*cite journal | author=Chung DW, Zhang JA, Tan CK, "et al." |title=Primary structure of the catalytic subunit of human DNA polymerase delta and chromosomal location of the gene. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 24 |pages= 11197–201 |year= 1992 |pmid= 1722322 |doi=
*cite journal | author=Popanda O, Thielmann HW |title=The function of DNA polymerases in DNA repair synthesis of ultraviolet-irradiated human fibroblasts. |journal=Biochim. Biophys. Acta |volume=1129 |issue= 2 |pages= 155–60 |year= 1992 |pmid= 1730053 |doi=
*cite journal | author=Lee MY, Toomey NL |title=Human placental DNA polymerase delta: identification of a 170-kilodalton polypeptide by activity staining and immunoblotting. |journal=Biochemistry |volume=26 |issue= 4 |pages= 1076–85 |year= 1987 |pmid= 2436659 |doi=
*cite journal | author=Dresler SL, Gowans BJ, Robinson-Hill RM, Hunting DJ |title=Involvement of DNA polymerase delta in DNA repair synthesis in human fibroblasts at late times after ultraviolet irradiation. |journal=Biochemistry |volume=27 |issue= 17 |pages= 6379–83 |year= 1989 |pmid= 3146346 |doi=
*cite journal | author=Nishida C, Reinhard P, Linn S |title=DNA repair synthesis in human fibroblasts requires DNA polymerase delta. |journal=J. Biol. Chem. |volume=263 |issue= 1 |pages= 501–10 |year= 1988 |pmid= 3335506 |doi=
*cite journal | author=Hindges R, Hübscher U |title=Cloning, chromosomal localization, and interspecies interaction of mouse DNA polymerase delta small subunit (PolD2). |journal=Genomics |volume=44 |issue= 1 |pages= 45–51 |year= 1997 |pmid= 9286699 |doi= 10.1006/geno.1997.4838
*cite journal | author=Wu SM, Zhang P, Zeng XR, "et al." |title=Characterization of the p125 subunit of human DNA polymerase delta and its deletion mutants. Interaction with cyclin-dependent kinase-cyclins. |journal=J. Biol. Chem. |volume=273 |issue= 16 |pages= 9561–9 |year= 1998 |pmid= 9545286 |doi=
*cite journal | author=Coll JM, Hickey RJ, Cronkey EA, "et al." |title=Mapping specific protein-protein interactions within the core component of the breast cell DNA synthesome. |journal=Oncol. Res. |volume=9 |issue= 11-12 |pages= 629–39 |year= 1998 |pmid= 9563011 |doi=
*cite journal | author=Fox G, Popanda O, Thielmann HW |title=Evidence for reduced copying fidelity of DNA polymerases alpha, delta, and epsilon from Novikoff hepatoma cells. |journal=J. Cancer Res. Clin. Oncol. |volume=123 |issue= 11-12 |pages= 659–68 |year= 1998 |pmid= 9620226 |doi=
*cite journal | author=Kim ST, Lim DS, Canman CE, Kastan MB |title=Substrate specificities and identification of putative substrates of ATM kinase family members. |journal=J. Biol. Chem. |volume=274 |issue= 53 |pages= 37538–43 |year= 2000 |pmid= 10608806 |doi=
*cite journal | author=Mo J, Liu L, Leon A, "et al." |title=Evidence that DNA polymerase delta isolated by immunoaffinity chromatography exhibits high-molecular weight characteristics and is associated with the KIAA0039 protein and RPA. |journal=Biochemistry |volume=39 |issue= 24 |pages= 7245–54 |year= 2000 |pmid= 10852724 |doi=
*cite journal | author=Budworth H, Dianova II, Podust VN, Dianov GL |title=Repair of clustered DNA lesions. Sequence-specific inhibition of long-patch base excision repair be 8-oxoguanine. |journal=J. Biol. Chem. |volume=277 |issue= 24 |pages= 21300–5 |year= 2002 |pmid= 11923315 |doi= 10.1074/jbc.M201918200
*cite journal | author=Ohta S, Shiomi Y, Sugimoto K, "et al." |title=A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein. |journal=J. Biol. Chem. |volume=277 |issue= 43 |pages= 40362–7 |year= 2002 |pmid= 12171929 |doi= 10.1074/jbc.M206194200
*cite journal | author=Smith RW, Nasheuer HP |title=Control of complex formation of DNA polymerase alpha-primase and cell-free DNA replication by the C-terminal amino acids of the largest subunit p180. |journal=FEBS Lett. |volume=527 |issue= 1-3 |pages= 143–6 |year= 2002 |pmid= 12220650 |doi=
*cite journal | author=Matheos D, Ruiz MT, Price GB, Zannis-Hadjopoulos M |title=Ku antigen, an origin-specific binding protein that associates with replication proteins, is required for mammalian DNA replication. |journal=Biochim. Biophys. Acta |volume=1578 |issue= 1-3 |pages= 59–72 |year= 2002 |pmid= 12393188 |doi=
*cite journal | author=Xie B, Mazloum N, Liu L, "et al." |title=Reconstitution and characterization of the human DNA polymerase delta four-subunit holoenzyme. |journal=Biochemistry |volume=41 |issue= 44 |pages= 13133–42 |year= 2002 |pmid= 12403614 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Shevelev IV, Ramadan K, Hübscher U |title=The TREX2 3'-->5' exonuclease physically interacts with DNA polymerase delta and increases its accuracy. |journal=ScientificWorldJournal |volume=2 |issue= |pages= 275–81 |year= 2004 |pmid= 12806015 |doi= 10.1100/tsw.2002.99

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • Eukaryotic DNA replication — Although the mechanisms of DNA synthesis in eukaryotes and prokaryotes are similar, DNA replication in eukaryotes is much more complicated. Though DNA synthesis in prokaryotes such as E. coli is regulated, DNA replication is initiated before the… …   Wikipedia

  • DNA polymerase delta — is an enzyme complex found in eukaryotes that is involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen (PCNA), the multisubunit replication factor C, and the 4 subunit polymerase complex: POLD1, POLD2,… …   Wikipedia

  • DNA ligase — repairing chromosomal damage Identifiers EC number 6.5.1.1 …   Wikipedia

  • DNA replication — DNA replication. The double helix is unwound and each strand acts as a template for the next strand. Bases are matched to synthesize the new partner strands. DNA replication is a biological process that occurs in all living organisms and copies… …   Wikipedia

  • Polymerase — Structure of Taq DNA polymerase A polymerase (EC 2.7.7.6/7/19/48/49) is an enzyme whose central function is associated with polymers of nucleic acids such as RNA and DNA. The primary function of a polymerase is the polymerization of new DNA or… …   Wikipedia

  • Primer (molecular biology) — A primer is a strand of nucleic acid that serves as a starting point for DNA synthesis. They are required for DNA replication because the enzymes that catalyze this process, DNA polymerases, can only add new nucleotides to an existing strand of… …   Wikipedia

  • DNA polymerase — 3D structure of the DNA binding helix turn helix motifs in human DNA polymerase beta A DNA polymerase is an enzyme that helps catalyze in the polymerization of deoxyribonucleotides into a DNA strand. DNA polymerases are best known for their… …   Wikipedia

  • Topoisomerase — Topoisomerases (type I: EC 5.99.1.2, type II: EC 5.99.1.3) are enzymes that regulate the overwinding or underwinding of DNA. The winding problem of DNA arises due to the intertwined nature of its double helical structure. For example, during DNA… …   Wikipedia

  • Primase — DNA primase is an enzyme involved in the replication of DNA. Primase catalyzes the synthesis of a short RNA (or DNA in some organisms [1]) segment called a primer complementary to a ssDNA template. Primase is of key importance in DNA replication… …   Wikipedia

  • Helicase — Structure of E. coli helicase RuvA Helicases are a class of enzymes vital to all living organisms. They are motor proteins that move directionally along a nucleic acid phosphodiester backbone, separating two annealed nucleic acid strands (i.e.,… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”