DNA damage-binding protein

damage-specific DNA binding protein 1, 127kDa
Identifiers
Symbol	DDB1
Alt. symbols	XPE
Entrez	1642
HUGO	2717
OMIM	600045
RefSeq	NM_001923
UniProt	Q16531
Other data
Locus	Chr. 11 q12-q13

damage-specific DNA binding protein 2, 48kDa
Identifiers
Symbol	DDB2
Alt. symbols	DBB, UV-DDB2, FLJ34321
Entrez	1643
HUGO	2718
OMIM	600811
RefSeq	NM_000107
UniProt	Q92466
Other data
Locus	Chr. 11 p12-p11

DNA damage-binding protein is a protein complex that is responsible for repair of UV-damaged DNA.^[1] This complex is composed of two protein subunits, a large subunit DDB1 and a small subunit DDB2. This complex functions in nucleotide excision repair.

References

1. ^ Dualan R, Brody T, Keeney S, Nichols AF, Admon A, Linn S (Feb 1996). "Chromosomal localization and cDNA cloning of the genes (DDB1 and DDB2) for the p127 and p48 subunits of a human damage-specific DNA binding protein". Genomics 29 (1): 62–9. doi:10.1006/geno.1995.1215. PMID 8530102. 

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