DIDS

DIDS
IUPAC name 5-Isothiocyanato-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]benzene-1-sulfonic acid
Other names 5-Isothiocyanato-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]benzenesulfonic acid
Identifiers
Abbreviations	DIDS
CAS number	53005-05-3 (E) Y
PubChem	40600, 5281951 (E), 9548709 (Z)
ChemSpider	37094 Y, 4445228 (E) Y, 7827632 (Z) Y
KEGG	C11591
MeSH	4,4'-Diisothiocyanostilbene-2,2'-disulfonic+acid
ChEBI	CHEBI:36511
Beilstein Reference	6543839
Jmol-3D images	Image 1
SMILES OS(=O)(=O)C1=C(C=CC2=C(C=C(C=C2)N=C=S)S(O)(=O)=O)C=CC(=C1)N=C=S
InChI InChI=1S/C16H10N2O6S4/c19-27(20,21)15-7-13(17-9-25)5-3-11(15)1-2-12-4-6-14(18-10-26)8-16(12)28(22,23)24/h1-8H,(H,19,20,21)(H,22,23,24) Key: YSCNMFDFYJUPEF-UHFFFAOYSA-N
Properties
Molecular formula	C16H10N2O6S4
Molar mass	454.52 g mol−1
Exact mass	453.942168822 g mol-1
Melting point	400 °C, 673 K, 752 °F
log P	4.72
Acidity (pKa)	-3.21, -1.428, -0.37, 0.23
Basicity (pKb)	13.77, 14.37, 15.425, 17.21
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid (DIDS) is an anion exchange inhibitor,^[1] blocking reversibly, and later irreversibly, exchangers such as chloride-bicarbonate exchanger.^[2]

References

1. ^ Jessen, Flemming; Sjøholm, C; Hoffmann, EK (1986), "Identification of the anion exchange protein of ehrlich cells: A kinetic analysis of the inhibitory effects of 4,4′-diisothiocyano-2,2′-stilbene-disulfonic acid (DIDS) and labeling of membrane proteins with3H-DIDS", Journal of Membrane Biology 92 (3): 195, doi:10.1007/BF01869388, PMID 3783658 
2. ^ Lane, Michelle; Baltz, Jay M.; Bavister, Barry D. (1999), "Bicarbonate/Chloride Exchange Regulates Intracellular pH of Embryos but Not Oocytes of the Hamster", Biology of Reproduction 61 (2): 452–457, doi:10.1095/biolreprod61.2.452, PMID 10411526 

This article about an organic compound is a stub. You can help Wikipedia by expanding it.v · Categories: Organic compound stubs Sulfonic acids Isothiocyanates Wikimedia Foundation. 2010. Игры ⚽ Поможем решить контрольную работу Diisodecyl phthalate Divo Airport Look at other dictionaries: DIDS — DIDS …   Википедия Dids — 4,4 diisothiocyano 2,2 stillbene disulfonic acid (DIDS) is an anion exchange inhibitor citation last = Jessen | first = Flemming year = 1986 title = Identification of the anion exchange protein of ehrlich cells: A kinetic analysis of the… …   Wikipedia DIDS — Defense Intelligence Dissemination System …   Military dictionary DIDS — Defense Integrated Data System (Governmental » Military) *** 4,4 diisothiocyanostilbene 2,2 disulfonic Acid (Academic & Science » Chemistry) …   Abbreviations dictionary DIDS — 4,4´diisothiocyanostilbene 2,2 disulfonate …   Medical dictionary DIDS — • Distributed Intrusion Detection System, Projekt an der Univ. of California Davis u.a. im Verbund mit der U.S. Air Force zur Erkennung und Meldung von möglichen Eindringungsversuchen ( > IEEE Networds, May/June 1994 Vol.8 No.3 ) • Defense… …   Acronyms DIDS — [1] Distributed Intrusion Detection System, Projekt an der Univ. of California Davis u.a. im Verbund mit der U.S. Air Force zur Erkennung und Meldung von möglichen Eindringungsversuchen ( > IEEE Networds, May/June 1994 Vol.8 No.3 ) [2] Defense …   Acronyms von A bis Z DIDS — • Defense Integrated Data System …   Maritime acronyms and abbreviations DIDS — • 4,4´diisothiocyanostilbene 2,2 disulfonate …   Dictionary of medical acronyms & abbreviations DIDS — comp. abbr. Digital Information Display System inf. abbr. Digital Information Display System comp. abbr. Distributed Intrusion Detection System …   United dictionary of abbreviations and acronyms 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”