Intracellular pH

Intracellular pH

All cells contain an intracellular fluid which has a pH value — this is known as the intracellular pH (pHi). The pHi of cells plays a critical role in their function and close regulation is required for cells to survive. There are numerous mechanisms that can cause pHi to change, including metabolic acid production, leakage of acid across plasma and organelle membranes and membrane transport processes. The mechanisms that regulate pHi are usually considered to be plasma membrane transporters of which two main types exist — those independent of HCO3– and those requiring HCO3–.


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  • Intracellular — In tra*cel lu*lar, a. (Biol.) Within a cell; as, the intracellular movements seen in the pigment cells, the salivary cells, and in the protoplasm of some vegetable cells; intracellular enzymes. Contrasted with {extracellular}. [1913 Webster +PJC] …   The Collaborative International Dictionary of English

  • intracellular — 1876, from INTRA (Cf. intra ) + CELLULAR (Cf. cellular) …   Etymology dictionary

  • intracellular — [in΄trə sel′yo͞o lər] adj. existing or occurring within a cell …   English World dictionary

  • intracellular — Within a cell or cells. * * * in·tra·cel·lu·lar sel yə lər adj existing, occurring, or functioning within a cell <intracellular enzymes> <intracellular localization of RNA synthesis> <intracellular parasites>… …   Medical dictionary

  • intracellular — adjective Date: 1876 existing, occurring, or functioning within a cell < intracellular parasites > • intracellularly adverb …   New Collegiate Dictionary

  • Intracellular — Not to be confused with intercellular, meaning between cells . In cell biology, molecular biology and related fields, the word intracellular means inside the cell . It is used in contrast to extracellular (outside the cell). The cell membrane… …   Wikipedia

  • intracellular — adjective Inside or within a cell. an intracellular process Ant: extracellular …   Wiktionary

  • Intracellular parasite — Intracellular parasites are parasitic microorganisms microparasites that are capable of growing and reproducing inside the cells of a host. Facultative Facultative intracellular parasites are capable of living and reproducing either inside or… …   Wikipedia

  • Intracellular receptor — Intracellular receptors are receptors located inside the cell rather than on its cell membrane. Examples are the class of nuclear receptors located in the cell nucleus and the IP3 receptor located on the endoplasmic reticulum. The ligands that… …   Wikipedia

  • Intracellular calcium-sensing proteins — are proteins that act in the second messenger system. Examples include: calmodulin calnexin calreticulin gelsolin External links MeSH Intracellular+Calcium Sensing+Proteins …   Wikipedia

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