- Dicobalt edetate
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Dicobalt edetate Other namesKelocyanorIdentifiers CAS number 36499-65-7 PubChem 71942 ChemSpider 64951 Jmol-3D images Image 1
Image 2- C(CN(CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].[Co+2].[Co+2]
[Co+2].[Co+2].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O
- InChI=1S/C10H16N2O8.2Co/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;/q;2*+2/p-4
Key: TWAWHTJKASJPEK-UHFFFAOYSA-J
InChI=1/C10H16N2O8.2Co/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;/q;2*+2/p-4
Key: TWAWHTJKASJPEK-XBHQNQODAQ
Properties Molecular formula C10H12Co2N2O8.6H2O Molar mass 406.08 g/mol
514.18 g/mol (hexahydrate)edetate (verify) (what is: / ?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)Infobox references Dicobalt edetate is the coordination compound with the approximate formula Co2(EDTA)(H2O)6.
Solutions of this solid have been used in Europe as an antidote to cyanide poisoning.[1]
It is a derivative of the (non-natural) amino acid ethylenediaminetetraacetate.
Structure
The compound is polymeric in the crystalline form. Half of the Co2+ ions are bound to the EDTA2− and the other Co2+ ions are bound to four water ligands as well as carboxylate ligands on the [Co(EDTA)]2− entity.[2] In aqueous solution, depolymerization occurs to give [Co(EDTA)]2− and [Co(H2O)6]2+ ions, each of which is kinetically labile and has a high affinity for cyanide. Oxidants would convert the [Co(EDTA)]2− into [Co(EDTA)]−, which would be unreactive toward cyanide because this complex would be "inert."[3]
References
- ^ Pickering WG (December 1985). "Cyanide toxicity and the hazards of dicobalt edetate". Br Med J (Clin Res Ed) 291 (6509): 1644. doi:10.1136/bmj.291.6509.1644-a. PMC 1418389. PMID 2866807. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1418389.
- ^ E. F. K. Mccandlish, T. K. Michael; Rose, N. J.; Neal, J. A.; Lingafelter, E. C.; Rose, N. J. (1978). "Comparison of the Structures and Aqueous Solutions of [(O-Phenylenediaminetetraacetato(2-)]Cobalt(II) and [Ethylenediaminetetraacetato(2-)]Cobalt(II)". Inorg. Chem. 17 (6): 1383–94. doi:10.1021/ic50184a001.
- ^ Dwyer, F. P.; Garvan, F. L.; Kirschner, Stanley (1960). "Resolution of the Ethylenediaminetetracetatocobaltate(III) Ion". Inorg. Synth.. Inorganic Syntheses 4: 192–4. doi:10.1002/9780470132371.ch61. ISBN 9780470132371.
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