MAP3K13

MAP3K13

Mitogen-activated protein kinase kinase kinase 13, also known as MAP3K13, is a human gene.cite web | title = Entrez Gene: MAP3K13 mitogen-activated protein kinase kinase kinase 13| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9175| accessdate = ]

PBB_Summary
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summary_text = The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway.cite web | title = Entrez Gene: MAP3K13 mitogen-activated protein kinase kinase kinase 13| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9175| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Masaki M, Ikeda A, Shiraki E, "et al." |title=Mixed lineage kinase LZK and antioxidant protein-1 activate NF-kappaB synergistically. |journal=Eur. J. Biochem. |volume=270 |issue= 1 |pages= 76-83 |year= 2003 |pmid= 12492477 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ikeda A, Sakuma H, Masaki M, "et al." |title=Genomic organization and fine-mapping of the human leucine zipper-bearing kinase (LZK) gene. |journal=J. Biochem. Mol. Biol. Biophys. |volume=6 |issue= 2 |pages= 113-7 |year= 2002 |pmid= 12186766 |doi= 10.1080/10258140290027243
*cite journal | author=Ikeda A, Hasegawa K, Masaki M, "et al." |title=Mixed lineage kinase LZK forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH(2)-terminal kinase pathway. |journal=J. Biochem. |volume=130 |issue= 6 |pages= 773-81 |year= 2002 |pmid= 11726277 |doi=
*cite journal | author=Ikeda A, Masaki M, Kozutsumi Y, "et al." |title=Identification and characterization of functional domains in a mixed lineage kinase LZK. |journal=FEBS Lett. |volume=488 |issue= 3 |pages= 190-5 |year= 2001 |pmid= 11163770 |doi=
*cite journal | author=Sakuma H, Ikeda A, Oka S, "et al." |title=Molecular cloning and functional expression of a cDNA encoding a new member of mixed lineage protein kinase from human brain. |journal=J. Biol. Chem. |volume=272 |issue= 45 |pages= 28622-9 |year= 1997 |pmid= 9353328 |doi=
*cite journal | author=Schultz SJ, Nigg EA |title=Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans. |journal=Cell Growth Differ. |volume=4 |issue= 10 |pages= 821-30 |year= 1994 |pmid= 8274451 |doi=

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