MYOM2

Myomesin (M-protein) 2, 165kDa, also known as MYOM2, is a human gene.cite web | title = Entrez Gene: MYOM2 myomesin (M-protein) 2, 165kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9172| accessdate = ]

PBB_Summary
section_title =
summary_text = The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical.cite web | title = Entrez Gene: MYOM2 myomesin (M-protein) 2, 165kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9172| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711-8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=Hornemann T, Kempa S, Himmel M, "et al." |title=Muscle-type creatine kinase interacts with central domains of the M-band proteins myomesin and M-protein. |journal=J. Mol. Biol. |volume=332 |issue= 4 |pages= 877-87 |year= 2003 |pmid= 12972258 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=van der Ven PF, Speel EJ, Albrechts JC, "et al." |title=Assignment of the human gene for endosarcomeric cytoskeletal M-protein (MYOM2) to 8p23.3. |journal=Genomics |volume=55 |issue= 2 |pages= 253-5 |year= 1999 |pmid= 9933576 |doi= 10.1006/geno.1998.5603
*cite journal | author=Obermann WM, van der Ven PF, Steiner F, "et al." |title=Mapping of a myosin-binding domain and a regulatory phosphorylation site in M-protein, a structural protein of the sarcomeric M band. |journal=Mol. Biol. Cell |volume=9 |issue= 4 |pages= 829-40 |year= 1998 |pmid= 9529381 |doi=
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791-806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Vinkemeier U, Obermann W, Weber K, Fürst DO |title=The globular head domain of titin extends into the center of the sarcomeric M band. cDNA cloning, epitope mapping and immunoelectron microscopy of two titin-associated proteins. |journal=J. Cell. Sci. |volume=106 ( Pt 1) |issue= |pages= 319-30 |year= 1994 |pmid= 7505783 |doi=

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