Florida State Road 66

Infobox road
state=FL
name_notes=
type=FL
route=66
length_mi=25
length_km=
established=
direction_a=West
direction_b=East
starting_terminus=
ending_terminus=
previous_type=FL
previous_route=65
next_type=FL
next_route=68

State Road 66 is a 25-mile-long east-west highway in Hardee County and Highlands County. Its western terminus is an intersection with US 17 (SR 35) in Zolfo Springs; the eastern terminus is an intersection with US 27-98 (SR 25-700) near De Soto City. The eastern continuation of SR 66 is eastbound US 98-SR 700 toward Okeechobee and West Palm Beach.

State Road 66 snakes through farmlands, woodlands, and wetlands in a sparsely-populated region of southern Florida. Near Crewsville, SR 66 provides access ("via" South Hammock Road, Washington Road, and Hammock Road) to Highlands Hammock State Park. It is part of what's known as the Florida Cracker Trail.