NXF2

NXF2
Nuclear RNA export factor 2
Identifiers
Symbols NXF2; CT39; FLJ20416; NXF2B; TAPL-2
External IDs OMIM300315 MGI2159343 HomoloGene88604 GeneCards: NXF2 Gene
Orthologs
Species Human Mouse
Entrez 56001 170722
Ensembl n/a ENSMUSG00000031410
UniProt Q9GZY0 n/a
RefSeq (mRNA) NM_017809.3 NM_130888.1
RefSeq (protein) NP_060279.2 NP_570958.1
Location (UCSC) n/a Chr X:
132.11 – 132.13 Mb
PubMed search [1] [2]

Nuclear RNA export factor 2 is a protein that in humans is encoded by the NXF2 gene.[1][2][3]

This gene is one of a family of nuclear RNA export factor genes. It encodes a protein that is involved in mRNA export, is located in the nucleoplasm, and is associated with the nuclear envelope. Alternative splicing seems to be a common mechanism in this gene family. Two variants have been found for this gene.[3]

Interactions

NXF2 has been shown to interact with NUP214.[1]

References

  1. ^ a b Herold A, Suyama M, Rodrigues JP, Braun IC, Kutay U, Carmo-Fonseca M, Bork P, Izaurralde E (Dec 2000). "TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture". Mol Cell Biol 20 (23): 8996–9008. doi:10.1128/MCB.20.23.8996-9008.2000. PMC 86553. PMID 11073998. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=86553. 
  2. ^ Wang PJ, McCarrey JR, Yang F, Page DC (Mar 2001). "An abundance of X-linked genes expressed in spermatogonia". Nat Genet 27 (4): 422–426. doi:10.1038/86927. PMID 11279525. 
  3. ^ a b "Entrez Gene: NXF2 nuclear RNA export factor 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56001. 

Further reading