TESK1

Testis-specific kinase 1, also known as TESK1, is a human gene.cite web | title = Entrez Gene: TESK1 testis-specific kinase 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7016| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis.cite web | title = Entrez Gene: TESK1 testis-specific kinase 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7016| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Toshima J, Ohashi K, Okano I, "et al." |title=Identification and characterization of a novel protein kinase, TESK1, specifically expressed in testicular germ cells. |journal=J. Biol. Chem. |volume=270 |issue= 52 |pages= 31331–7 |year= 1996 |pmid= 8537404 |doi=
*cite journal | author=Toshima J, Tanaka T, Mizuno K |title=Dual specificity protein kinase activity of testis-specific protein kinase 1 and its regulation by autophosphorylation of serine-215 within the activation loop. |journal=J. Biol. Chem. |volume=274 |issue= 17 |pages= 12171–6 |year= 1999 |pmid= 10207045 |doi=
*cite journal | author=Røsok O, Pedeutour F, Ree AH, Aasheim HC |title=Identification and characterization of TESK2, a novel member of the LIMK/TESK family of protein kinases, predominantly expressed in testis. |journal=Genomics |volume=61 |issue= 1 |pages= 44–54 |year= 1999 |pmid= 10512679 |doi= 10.1006/geno.1999.5922
*cite journal | author=Toshima J, Toshima JY, Amano T, "et al." |title=Cofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formation. |journal=Mol. Biol. Cell |volume=12 |issue= 4 |pages= 1131–45 |year= 2001 |pmid= 11294912 |doi=
*cite journal | author=Toshima J, Toshima JY, Takeuchi K, "et al." |title=Cofilin phosphorylation and actin reorganization activities of testicular protein kinase 2 and its predominant expression in testicular Sertoli cells. |journal=J. Biol. Chem. |volume=276 |issue= 33 |pages= 31449–58 |year= 2001 |pmid= 11418599 |doi= 10.1074/jbc.M102988200
*cite journal | author=Toshima JY, Toshima J, Watanabe T, Mizuno K |title=Binding of 14-3-3beta regulates the kinase activity and subcellular localization of testicular protein kinase 1. |journal=J. Biol. Chem. |volume=276 |issue= 46 |pages= 43471–81 |year= 2001 |pmid= 11555644 |doi= 10.1074/jbc.M104620200
*cite journal | author=Leeksma OC, Van Achterberg TA, Tsumura Y, "et al." |title=Human sprouty 4, a new ras antagonist on 5q31, interacts with the dual specificity kinase TESK1. |journal=Eur. J. Biochem. |volume=269 |issue= 10 |pages= 2546–56 |year= 2002 |pmid= 12027893 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=LaLonde DP, Brown MC, Bouverat BP, Turner CE |title=Actopaxin interacts with TESK1 to regulate cell spreading on fibronectin. |journal=J. Biol. Chem. |volume=280 |issue= 22 |pages= 21680–8 |year= 2005 |pmid= 15817463 |doi= 10.1074/jbc.M500752200
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209

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