LILRA2

LILRA2

Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2, also known as LILRA2, is a human gene.cite web | title = Entrez Gene: LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11027| accessdate = ]

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summary_text = Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades. One member of subfamily A (LILRA3; MIM 604818) lacks a transmembrane region and is presumed to be a soluble receptor. [supplied by OMIM] cite web | title = Entrez Gene: LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11027| accessdate = ]

ee also

* Cluster of differentiation

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Rojo S, Burshtyn DN, Long EO, Wagtmann N |title=Type I transmembrane receptor with inhibitory function in mouse mast cells and NK cells. |journal=J. Immunol. |volume=158 |issue= 1 |pages= 9–12 |year= 1997 |pmid= 8977169 |doi=
*cite journal | author=Samaridis J, Colonna M |title=Cloning of novel immunoglobulin superfamily receptors expressed on human myeloid and lymphoid cells: structural evidence for new stimulatory and inhibitory pathways. |journal=Eur. J. Immunol. |volume=27 |issue= 3 |pages= 660–5 |year= 1997 |pmid= 9079806 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Borges L, Hsu ML, Fanger N, "et al." |title=A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules. |journal=J. Immunol. |volume=159 |issue= 11 |pages= 5192–6 |year= 1998 |pmid= 9548455 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Tedla N, Bandeira-Melo C, Tassinari P, "et al." |title=Activation of human eosinophils through leukocyte immunoglobulin-like receptor 7. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 3 |pages= 1174–9 |year= 2003 |pmid= 12529506 |doi= 10.1073/pnas.0337567100
*cite journal | author=Nakajima H, Asai A, Okada A, "et al." |title=Transcriptional regulation of ILT family receptors. |journal=J. Immunol. |volume=171 |issue= 12 |pages= 6611–20 |year= 2004 |pmid= 14662864 |doi=
*cite journal | author=Sloane DE, Tedla N, Awoniyi M, "et al." |title=Leukocyte immunoglobulin-like receptors: novel innate receptors for human basophil activation and inhibition. |journal=Blood |volume=104 |issue= 9 |pages= 2832–9 |year= 2004 |pmid= 15242876 |doi= 10.1182/blood-2004-01-0268
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

External links

*

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