CDH11

Cadherin 11, type 2, OB-cadherin (osteoblast), also known as CDH11, is a human gene.cite web | title = Entrez Gene: CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1009| accessdate = ]

PBB_Summary
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summary_text = This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.cite web | title = Entrez Gene: CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1009| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Suzuki S, Sano K, Tanihara H |title=Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue. |journal=Cell Regul. |volume=2 |issue= 4 |pages= 261–70 |year= 1991 |pmid= 2059658 |doi=
*cite journal | author=Tanihara H, Sano K, Heimark RL, "et al." |title=Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin. |journal=Cell Adhes. Commun. |volume=2 |issue= 1 |pages= 15–26 |year= 1995 |pmid= 7982033 |doi=
*cite journal | author=Okazaki M, Takeshita S, Kawai S, "et al." |title=Molecular cloning and characterization of OB-cadherin, a new member of cadherin family expressed in osteoblasts. |journal=J. Biol. Chem. |volume=269 |issue= 16 |pages= 12092–8 |year= 1994 |pmid= 8163513 |doi=
*cite journal | author=Getsios S, Chen GT, Stephenson MD, "et al." |title=Regulated expression of cadherin-6 and cadherin-11 in the glandular epithelial and stromal cells of the human endometrium. |journal=Dev. Dyn. |volume=211 |issue= 3 |pages= 238–47 |year= 1998 |pmid= 9520111 |doi= 10.1002/(SICI)1097-0177(199803)211:3<238::AID-AJA5>3.0.CO;2-I |doilabel=10.1002/(SICI)1097-0177(199803)211:3238::AID-AJA53.0.CO;2-I
*cite journal | author=Kremmidiotis G, Baker E, Crawford J, "et al." |title=Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity. |journal=Genomics |volume=49 |issue= 3 |pages= 467–71 |year= 1998 |pmid= 9615235 |doi= 10.1006/geno.1998.5281
*cite journal | author=Pishvaian MJ, Feltes CM, Thompson P, "et al." |title=Cadherin-11 is expressed in invasive breast cancer cell lines. |journal=Cancer Res. |volume=59 |issue= 4 |pages= 947–52 |year= 1999 |pmid= 10029089 |doi=
*cite journal | author=Kawaguchi J, Takeshita S, Kashima T, "et al." |title=Expression and function of the splice variant of the human cadherin-11 gene in subordination to intact cadherin-11. |journal=J. Bone Miner. Res. |volume=14 |issue= 5 |pages= 764–75 |year= 1999 |pmid= 10320525 |doi=
*cite journal | author=Braungart E, Schumacher C, Hartmann E, "et al." |title=Functional loss of E-cadherin and cadherin-11 alleles on chromosome 16q22 in colonic cancer. |journal=J. Pathol. |volume=187 |issue= 5 |pages= 530–4 |year= 2000 |pmid= 10398117 |doi= 10.1002/(SICI)1096-9896(199904)187:5<530::AID-PATH293>3.0.CO;2-C |doilabel=10.1002/(SICI)1096-9896(199904)187:5530::AID-PATH2933.0.CO;2-C
*cite journal | author=Kashima T, Kawaguchi J, Takeshita S, "et al." |title=Anomalous cadherin expression in osteosarcoma. Possible relationships to metastasis and morphogenesis. |journal=Am. J. Pathol. |volume=155 |issue= 5 |pages= 1549–55 |year= 1999 |pmid= 10550312 |doi=
*cite journal | author=Lecanda F, Cheng SL, Shin CS, "et al." |title=Differential regulation of cadherins by dexamethasone in human osteoblastic cells. |journal=J. Cell. Biochem. |volume=77 |issue= 3 |pages= 499–506 |year= 2000 |pmid= 10760957 |doi=
*cite journal | author=Braungart E, Hartman E, Bechler K, "et al." |title=The intracellular domain of cadherin-11 is not required for the induction of cell aggregation, adhesion or gap-junction formation. |journal=Cell Commun. Adhes. |volume=8 |issue= 1 |pages= 15–27 |year= 2002 |pmid= 11775026 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Straub BK, Boda J, Kuhn C, "et al." |title=A novel cell-cell junction system: the cortex adhaerens mosaic of lens fiber cells. |journal=J. Cell. Sci. |volume=116 |issue= Pt 24 |pages= 4985–95 |year= 2004 |pmid= 14625392 |doi= 10.1242/jcs.00815
*cite journal | author=Morimoto AM, Tan N, West K, "et al." |title=Gene expression profiling of human colon xenograft tumors following treatment with SU11248, a multitargeted tyrosine kinase inhibitor. |journal=Oncogene |volume=23 |issue= 8 |pages= 1618–26 |year= 2004 |pmid= 14985702 |doi= 10.1038/sj.onc.1207268
*cite journal | author=Marchong MN, Chen D, Corson TW, "et al." |title=Minimal 16q genomic loss implicates cadherin-11 in retinoblastoma. |journal=Mol. Cancer Res. |volume=2 |issue= 9 |pages= 495–503 |year= 2005 |pmid= 15383628 |doi=
*cite journal | author=Oliveira AM, Perez-Atayde AR, Inwards CY, "et al." |title=USP6 and CDH11 oncogenes identify the neoplastic cell in primary aneurysmal bone cysts and are absent in so-called secondary aneurysmal bone cysts. |journal=Am. J. Pathol. |volume=165 |issue= 5 |pages= 1773–80 |year= 2004 |pmid= 15509545 |doi=
*cite journal | author=Kiener HP, Brenner MB |title=Building the synovium: cadherin-11 mediates fibroblast-like synoviocyte cell-to-cell adhesion. |journal=Arthritis Res. Ther. |volume=7 |issue= 2 |pages= 49–54 |year= 2005 |pmid= 15743489 |doi= 10.1186/ar1495
*cite journal | author=Kiener HP, Lee DM, Agarwal SK, Brenner MB |title=Cadherin-11 induces rheumatoid arthritis fibroblast-like synoviocytes to form lining layers in vitro. |journal=Am. J. Pathol. |volume=168 |issue= 5 |pages= 1486–99 |year= 2006 |pmid= 16651616 |doi=

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