SCARB2

Scavenger receptor class B, member 2, also known as SCARB2, is a human gene.cite web | title = Entrez Gene: SCARB2 scavenger receptor class B, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=950| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Studies of the similar protein in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. Deficiency of the similar protein in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy.cite web | title = Entrez Gene: SCARB2 scavenger receptor class B, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=950| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Eskelinen EL, Tanaka Y, Saftig P |title=At the acidic edge: emerging functions for lysosomal membrane proteins. |journal=Trends Cell Biol. |volume=13 |issue= 3 |pages= 137–45 |year= 2003 |pmid= 12628346 |doi=
*cite journal | author=Fujita H, Takata Y, Kono A, "et al." |title=Isolation and sequencing of a cDNA clone encoding the 85 kDa human lysosomal sialoglycoprotein (hLGP85) in human metastatic pancreas islet tumor cells. |journal=Biochem. Biophys. Res. Commun. |volume=184 |issue= 2 |pages= 604–11 |year= 1992 |pmid= 1374238 |doi=
*cite journal | author=Sandoval IV, Arredondo JJ, Alcalde J, "et al." |title=The residues Leu(Ile)475-Ile(Leu, Val, Ala)476, contained in the extended carboxyl cytoplasmic tail, are critical for targeting of the resident lysosomal membrane protein LIMP II to lysosomes. |journal=J. Biol. Chem. |volume=269 |issue= 9 |pages= 6622–31 |year= 1994 |pmid= 7509809 |doi=
*cite journal | author=Calvo D, Dopazo J, Vega MA |title=The CD36, CLA-1 (CD36L1), and LIMPII (CD36L2) gene family: cellular distribution, chromosomal location, and genetic evolution. |journal=Genomics |volume=25 |issue= 1 |pages= 100–6 |year= 1995 |pmid= 7539776 |doi=
*cite journal | author=Crombie R, Silverstein R |title=Lysosomal integral membrane protein II binds thrombospondin-1. Structure-function homology with the cell adhesion molecule CD36 defines a conserved recognition motif. |journal=J. Biol. Chem. |volume=273 |issue= 9 |pages= 4855–63 |year= 1998 |pmid= 9478926 |doi=
*cite journal | author=Harris RA, Yang A, Stein RC, "et al." |title=Cluster analysis of an extensive human breast cancer cell line protein expression map database. |journal=Proteomics |volume=2 |issue= 2 |pages= 212–23 |year= 2002 |pmid= 11840567 |doi=
*cite journal | author=Wistow G, Bernstein SL, Wyatt MK, "et al." |title=Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants. |journal=Mol. Vis. |volume=8 |issue= |pages= 205–20 |year= 2002 |pmid= 12107410 |doi=
*cite journal | author=Kuronita T, Eskelinen EL, Fujita H, "et al." |title=A role for the lysosomal membrane protein LGP85 in the biogenesis and maintenance of endosomal and lysosomal morphology. |journal=J. Cell. Sci. |volume=115 |issue= Pt 21 |pages= 4117–31 |year= 2003 |pmid= 12356916 |doi=
*cite journal | author=Rodionov DG, Höning S, Silye A, "et al." |title=Structural requirements for interactions between leucine-sorting signals and clathrin-associated adaptor protein complex AP3. |journal=J. Biol. Chem. |volume=277 |issue= 49 |pages= 47436–43 |year= 2003 |pmid= 12370188 |doi= 10.1074/jbc.M207149200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gamp AC, Tanaka Y, Lüllmann-Rauch R, "et al." |title=LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice. |journal=Hum. Mol. Genet. |volume=12 |issue= 6 |pages= 631–46 |year= 2003 |pmid= 12620969 |doi=
*cite journal | author=Zhang H, Li XJ, Martin DB, Aebersold R |title=Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. |journal=Nat. Biotechnol. |volume=21 |issue= 6 |pages= 660–6 |year= 2003 |pmid= 12754519 |doi= 10.1038/nbt827
*cite journal | author=Mulcahy JV, Riddell DR, Owen JS |title=Human scavenger receptor class B type II (SR-BII) and cellular cholesterol efflux. |journal=Biochem. J. |volume=377 |issue= Pt 3 |pages= 741–7 |year= 2004 |pmid= 14570588 |doi= 10.1042/BJ20030307
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Eckhardt ER, Cai L, Shetty S, "et al." |title=High density lipoprotein endocytosis by scavenger receptor SR-BII is clathrin-dependent and requires a carboxyl-terminal dileucine motif. |journal=J. Biol. Chem. |volume=281 |issue= 7 |pages= 4348–53 |year= 2006 |pmid= 16368683 |doi= 10.1074/jbc.M513154200
*cite journal | author=Gupta SN, Kloster MM, Rodionov DG, Bakke O |title=Re-routing of the invariant chain to the direct sorting pathway by introduction of an AP3-binding motif from LIMP II. |journal=Eur. J. Cell Biol. |volume=85 |issue= 6 |pages= 457–67 |year= 2007 |pmid= 16542748 |doi= 10.1016/j.ejcb.2006.02.001
*cite journal | author=Tserentsoodol N, Gordiyenko NV, Pascual I, "et al." |title=Intraretinal lipid transport is dependent on high density lipoprotein-like particles and class B scavenger receptors. |journal=Mol. Vis. |volume=12 |issue= |pages= 1319–33 |year= 2006 |pmid= 17110915 |doi=
*cite journal | author=Grove J, Huby T, Stamataki Z, "et al." |title=Scavenger receptor BI and BII expression levels modulate hepatitis C virus infectivity. |journal=J. Virol. |volume=81 |issue= 7 |pages= 3162–9 |year= 2007 |pmid= 17215280 |doi= 10.1128/JVI.02356-06

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