- GNB5
Guanine nucleotide binding protein (G protein), beta 5, also known as GNB5, is a human
gene .cite web | title = Entrez Gene: GNB5 guanine nucleotide binding protein (G protein), beta 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10681| accessdate = ]PBB_Summary
section_title =
summary_text = Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist.cite web | title = Entrez Gene: GNB5 guanine nucleotide binding protein (G protein), beta 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10681| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Downes GB, Gautam N |title=The G protein subunit gene families. |journal=Genomics |volume=62 |issue= 3 |pages= 544–52 |year= 2000 |pmid= 10644457 |doi= 10.1006/geno.1999.5992
*cite journal | author=Yan K, Kalyanaraman V, Gautam N |title=Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families. |journal=J. Biol. Chem. |volume=271 |issue= 12 |pages= 7141–6 |year= 1996 |pmid= 8636150 |doi=
*cite journal | author=Watson AJ, Aragay AM, Slepak VZ, Simon MI |title=A novel form of the G protein beta subunit Gbeta5 is specifically expressed in the vertebrate retina. |journal=J. Biol. Chem. |volume=271 |issue= 45 |pages= 28154–60 |year= 1996 |pmid= 8910430 |doi=
*cite journal | author=Gold SJ, Ni YG, Dohlman HG, Nestler EJ |title=Regulators of G-protein signaling (RGS) proteins: region-specific expression of nine subtypes in rat brain. |journal=J. Neurosci. |volume=17 |issue= 20 |pages= 8024–37 |year= 1997 |pmid= 9315921 |doi=
*cite journal | author=Jones PG, Lombardi SJ, Cockett MI |title=Cloning and tissue distribution of the human G protein beta 5 cDNA. |journal=Biochim. Biophys. Acta |volume=1402 |issue= 3 |pages= 288–91 |year= 1998 |pmid= 9606987 |doi=
*cite journal | author=Snow BE, Krumins AM, Brothers GM, "et al." |title=A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 22 |pages= 13307–12 |year= 1998 |pmid= 9789084 |doi=
*cite journal | author=Levay K, Cabrera JL, Satpaev DK, Slepak VZ |title=Gbeta5 prevents the RGS7-Galphao interaction through binding to a distinct Ggamma-like domain found in RGS7 and other RGS proteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 5 |pages= 2503–7 |year= 1999 |pmid= 10051672 |doi=
*cite journal | author=Snow BE, Betts L, Mangion J, "et al." |title=Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 11 |pages= 6489–94 |year= 1999 |pmid= 10339615 |doi=
*cite journal | author=Posner BA, Gilman AG, Harris BA |title=Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on g protein-mediated signaling pathways. |journal=J. Biol. Chem. |volume=274 |issue= 43 |pages= 31087–93 |year= 1999 |pmid= 10521509 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Wiemann S, Weil B, Wellenreuther R, "et al." |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701
*cite journal | author=Simpson JC, Wellenreuther R, Poustka A, "et al." |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287–92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058
*cite journal | author=Blake BL, Wing MR, Zhou JY, "et al." |title=G beta association and effector interaction selectivities of the divergent G gamma subunit G gamma(13). |journal=J. Biol. Chem. |volume=276 |issue= 52 |pages= 49267–74 |year= 2002 |pmid= 11675383 |doi= 10.1074/jbc.M106565200
*cite journal | author=Hu G, Wensel TG |title=R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 15 |pages= 9755–60 |year= 2002 |pmid= 12119397 |doi= 10.1073/pnas.152094799
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Ajit SK, Young KH |title=Enhancement of pheromone response by RGS9 and Gbeta5 in yeast. |journal=Biochem. Biophys. Res. Commun. |volume=324 |issue= 2 |pages= 686–91 |year= 2004 |pmid= 15474482 |doi= 10.1016/j.bbrc.2004.09.100
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Wiemann S, Arlt D, Huber W, "et al." |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704PBB_Controls
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