- GJA4
Gap junction protein, alpha 4, 37kDa, also known as GJA4, is a human
gene .cite web | title = Entrez Gene: GJA4 gap junction protein, alpha 4, 37kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2701| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.cite web | title = Entrez Gene: GJA4 gap junction protein, alpha 4, 37kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2701| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Beyer EC, Paul DL, Goodenough DA |title=Connexin family of gap junction proteins. |journal=J. Membr. Biol. |volume=116 |issue= 3 |pages= 187–94 |year= 1990 |pmid= 2167375 |doi=
*cite journal | author=Haefliger JA, Bruzzone R, Jenkins NA, "et al." |title=Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping. |journal=J. Biol. Chem. |volume=267 |issue= 3 |pages= 2057–64 |year= 1992 |pmid= 1370487 |doi=
*cite journal | author=Risek B, Guthrie S, Kumar N, Gilula NB |title=Modulation of gap junction transcript and protein expression during pregnancy in the rat. |journal=J. Cell Biol. |volume=110 |issue= 2 |pages= 269–82 |year= 1990 |pmid= 1688855 |doi=
*cite journal | author=Willecke K, Jungbluth S, Dahl E, "et al." |title=Six genes of the human connexin gene family coding for gap junctional proteins are assigned to four different human chromosomes. |journal=Eur. J. Cell Biol. |volume=53 |issue= 2 |pages= 275–80 |year= 1991 |pmid= 1964417 |doi=
*cite journal | author=Reed KE, Westphale EM, Larson DM, "et al." |title=Molecular cloning and functional expression of human connexin37, an endothelial cell gap junction protein. |journal=J. Clin. Invest. |volume=91 |issue= 3 |pages= 997–1004 |year= 1993 |pmid= 7680674 |doi=
*cite journal | author=Van Camp G, Coucke P, Speleman F, "et al." |title=The gene for human gap junction protein connexin37 (GJA4) maps to chromosome 1p35.1, in the vicinity of D1S195. |journal=Genomics |volume=30 |issue= 2 |pages= 402–3 |year= 1996 |pmid= 8586454 |doi=
*cite journal | author=Krutovskikh V, Mironov N, Yamasaki H |title=Human connexin 37 is polymorphic but not mutated in tumours. |journal=Carcinogenesis |volume=17 |issue= 8 |pages= 1761–3 |year= 1996 |pmid= 8761439 |doi=
*cite journal | author=Simon AM, Goodenough DA, Li E, Paul DL |title=Female infertility in mice lacking connexin 37. |journal=Nature |volume=385 |issue= 6616 |pages= 525–9 |year= 1997 |pmid= 9020357 |doi= 10.1038/385525a0
*cite journal | author=Krenacs T, Rosendaal M |title=Connexin43 gap junctions in normal, regenerating, and cultured mouse bone marrow and in human leukemias: their possible involvement in blood formation. |journal=Am. J. Pathol. |volume=152 |issue= 4 |pages= 993–1004 |year= 1998 |pmid= 9546360 |doi=
*cite journal | author=van Rijen HV, van Kempen MJ, Postma S, Jongsma HJ |title=Tumour necrosis factor alpha alters the expression of connexin43, connexin40, and connexin37 in human umbilical vein endothelial cells. |journal=Cytokine |volume=10 |issue= 4 |pages= 258–64 |year= 1998 |pmid= 9617570 |doi= 10.1006/cyto.1997.0287
*cite journal | author=Richard G, Smith LE, Bailey RA, "et al." |title=Mutations in the human connexin gene GJB3 cause erythrokeratodermia variabilis. |journal=Nat. Genet. |volume=20 |issue= 4 |pages= 366–9 |year= 1998 |pmid= 9843209 |doi= 10.1038/3840
*cite journal | author=Boerma M, Forsberg L, Van Zeijl L, "et al." |title=A genetic polymorphism in connexin 37 as a prognostic marker for atherosclerotic plaque development. |journal=J. Intern. Med. |volume=246 |issue= 2 |pages= 211–8 |year= 1999 |pmid= 10447790 |doi=
*cite journal | author=Saito T, Krutovskikh V, Marion MJ, "et al." |title=Human hemangiosarcomas have a common polymorphism but no mutations in the connexin37 gene. |journal=Int. J. Cancer |volume=86 |issue= 1 |pages= 67–70 |year= 2000 |pmid= 10728596 |doi=
*cite journal | author=Suzuki Y, Taira H, Tsunoda T, "et al." |title=Diverse transcriptional initiation revealed by fine, large-scale mapping of mRNA start sites. |journal=EMBO Rep. |volume=2 |issue= 5 |pages= 388–93 |year= 2001 |pmid= 11375929 |doi= 10.1093/embo-reports/kve085
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Tsai MY, Lan KC, Huang KE, "et al." |title=Significance of mRNA levels of connexin37, connexin43, and connexin45 in luteinized granulosa cells of controlled hyperstimulated follicles. |journal=Fertil. Steril. |volume=80 |issue= 6 |pages= 1437–43 |year= 2004 |pmid= 14667880 |doi=
*cite journal | author=Seul KH, Kang KY, Lee KS, "et al." |title=Adenoviral delivery of human connexin37 induces endothelial cell death through apoptosis. |journal=Biochem. Biophys. Res. Commun. |volume=319 |issue= 4 |pages= 1144–51 |year= 2004 |pmid= 15194487 |doi= 10.1016/j.bbrc.2004.05.097
*cite journal | author=Kameritsch P, Khandoga N, Nagel W, "et al." |title=Nitric oxide specifically reduces the permeability of Cx37-containing gap junctions to small molecules. |journal=J. Cell. Physiol. |volume=203 |issue= 1 |pages= 233–42 |year= 2005 |pmid= 15481066 |doi= 10.1002/jcp.20218
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes
Wikimedia Foundation. 2010.
