TNFRSF14

Tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator), also known as TNFRSF14, is a human gene.cite web | title = Entrez Gene: TNFRSF14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8764| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response.cite web | title = Entrez Gene: TNFRSF14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8764| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Montgomery RI, Warner MS, Lum BJ, Spear PG |title=Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family. |journal=Cell |volume=87 |issue= 3 |pages= 427–36 |year= 1996 |pmid= 8898196 |doi=
*cite journal | author=Hsu H, Solovyev I, Colombero A, "et al." |title=ATAR, a novel tumor necrosis factor receptor family member, signals through TRAF2 and TRAF5. |journal=J. Biol. Chem. |volume=272 |issue= 21 |pages= 13471–4 |year= 1997 |pmid= 9153189 |doi=
*cite journal | author=Marsters SA, Ayres TM, Skubatch M, "et al." |title=Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1. |journal=J. Biol. Chem. |volume=272 |issue= 22 |pages= 14029–32 |year= 1997 |pmid= 9162022 |doi=
*cite journal | author=Kwon BS, Tan KB, Ni J, "et al." |title=A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation. |journal=J. Biol. Chem. |volume=272 |issue= 22 |pages= 14272–6 |year= 1997 |pmid= 9162061 |doi=
*cite journal | author=Mauri DN, Ebner R, Montgomery RI, "et al." |title=LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator. |journal=Immunity |volume=8 |issue= 1 |pages= 21–30 |year= 1998 |pmid= 9462508 |doi=
*cite journal | author=Lee CH, Chinpaisal C, Wei LN |title=Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2. |journal=Mol. Cell. Biol. |volume=18 |issue= 11 |pages= 6745–55 |year= 1998 |pmid= 9774688 |doi=
*cite journal | author=Kelly K, Manos E, Jensen G, "et al." |title=APRIL/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death. |journal=Cancer Res. |volume=60 |issue= 4 |pages= 1021–7 |year= 2000 |pmid= 10706119 |doi=
*cite journal | author=Zhang J, Salcedo TW, Wan X, "et al." |title=Modulation of T-cell responses to alloantigens by TR6/DcR3. |journal=J. Clin. Invest. |volume=107 |issue= 11 |pages= 1459–68 |year= 2001 |pmid= 11390428 |doi=
*cite journal | author=Franco PJ, Farooqui M, Seto E, Wei LN |title=The orphan nuclear receptor TR2 interacts directly with both class I and class II histone deacetylases. |journal=Mol. Endocrinol. |volume=15 |issue= 8 |pages= 1318–28 |year= 2001 |pmid= 11463856 |doi=
*cite journal | author=Carfí A, Willis SH, Whitbeck JC, "et al." |title=Herpes simplex virus glycoprotein D bound to the human receptor HveA. |journal=Mol. Cell |volume=8 |issue= 1 |pages= 169–79 |year= 2001 |pmid= 11511370 |doi=
*cite journal | author=Bobik A, Kalinina N |title=Tumor necrosis factor receptor and ligand superfamily family members TNFRSF14 and LIGHT: new players in human atherogenesis. |journal=Arterioscler. Thromb. Vasc. Biol. |volume=21 |issue= 12 |pages= 1873–5 |year= 2002 |pmid= 11742858 |doi=
*cite journal | author=Struyf F, Posavad CM, Keyaerts E, "et al." |title=Search for polymorphisms in the genes for herpesvirus entry mediator, nectin-1, and nectin-2 in immune seronegative individuals. |journal=J. Infect. Dis. |volume=185 |issue= 1 |pages= 36–44 |year= 2002 |pmid= 11756979 |doi=
*cite journal | author=Carfí A, Gong H, Lou H, "et al." |title=Crystallization and preliminary diffraction studies of the ectodomain of the envelope glycoprotein D from herpes simplex virus 1 alone and in complex with the ectodomain of the human receptor HveA. |journal=Acta Crystallogr. D Biol. Crystallogr. |volume=58 |issue= Pt 5 |pages= 836–8 |year= 2002 |pmid= 11976496 |doi=
*cite journal | author=Hu YC, Shyr CR, Che W, "et al." |title=Suppression of estrogen receptor-mediated transcription and cell growth by interaction with TR2 orphan receptor. |journal=J. Biol. Chem. |volume=277 |issue= 37 |pages= 33571–9 |year= 2002 |pmid= 12093804 |doi= 10.1074/jbc.M203531200
*cite journal | author=Gill RM, Ni J, Hunt JS |title=Differential expression of LIGHT and its receptors in human placental villi and amniochorion membranes. |journal=Am. J. Pathol. |volume=161 |issue= 6 |pages= 2011–7 |year= 2003 |pmid= 12466117 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Bender FC, Whitbeck JC, Ponce de Leon M, "et al." |title=Specific association of glycoprotein B with lipid rafts during herpes simplex virus entry. |journal=J. Virol. |volume=77 |issue= 17 |pages= 9542–52 |year= 2003 |pmid= 12915568 |doi=
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Jung HW, La SJ, Kim JY, "et al." |title=High levels of soluble herpes virus entry mediator in sera of patients with allergic and autoimmune diseases. |journal=Exp. Mol. Med. |volume=35 |issue= 6 |pages= 501–8 |year= 2004 |pmid= 14749527 |doi=
*cite journal | author=Krummenacher C, Baribaud F, Ponce de Leon M, "et al." |title=Comparative usage of herpesvirus entry mediator A and nectin-1 by laboratory strains and clinical isolates of herpes simplex virus. |journal=Virology |volume=322 |issue= 2 |pages= 286–99 |year= 2004 |pmid= 15110526 |doi= 10.1016/j.virol.2004.02.005

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