(tyrosine 3-monooxygenase) kinase

(tyrosine 3-monooxygenase) kinase

In enzymology, a [tyrosine 3-monooxygenase] kinase (EC number|2.7.11.6) is an enzyme that catalyzes the chemical reaction

:ATP + [tyrosine-3-monooxygenase] ightleftharpoons ADP + phospho- [tyrosine-3-monooxygenase]

Thus, the two substrates of this enzyme are ATP and [tyrosine-3-monooxygenase] , whereas its two products are ADP and [phospho- [tyrosine-3-monooxygenase] .

This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases). The systematic name of this enzyme class is ATP: [tyrosine-3-monoxygenase] phosphotransferase. Other names in common use include pheochromocytoma tyrosine hydroxylase-associated kinase, STK4, and tyrosine 3-monooxygenase kinase (phosphorylating). This enzyme participates in mapk signaling pathway and non-small cell lung cancer.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|103537-12-8."

Gene Ontology (GO) codes


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