Low-density-lipoprotein receptor kinase

In enzymology, a low-density-lipoprotein receptor kinase (EC number|2.7.11.29) is an enzyme that catalyzes the chemical reaction

:ATP + [low-density-lipoprotein receptor] -L-serine $ightleftharpoons$ ADP + [low-density-lipoprotein receptor] -O-phospho-L-serine

Thus, the two substrates of this enzyme are ATP and [low-density-lipoprotein receptor] -L-serine, whereas its two products are ADP and [low-density-lipoprotein receptor] -O-phospho-L-serine.

This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases). The systematic name of this enzyme class is ATP: [low-density-lipoprotein receptor] -L-serine O-phosphotransferase. Other names in common use include ATP:low-density-lipoprotein-L-serine O-phosphotransferase, LDL receptor kinase, [low-density-lipoprotein] kinase, low-density lipoprotein kinase, low-density-lipoprotein receptor kinase (phosphorylating), and STK7.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|107445-00-1."

Gene Ontology (GO) codes