- D-ribitol-5-phosphate cytidylyltransferase
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D-ribitol-5-phosphate cytidylyltransferase Identifiers EC number 2.7.7.40 CAS number 9027-07-0 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a D-ribitol-5-phosphate cytidylyltransferase (EC 2.7.7.40) is an enzyme that catalyzes the chemical reaction
- CTP + D-ribitol 5-phosphate
diphosphate + CDP-ribitol
Thus, the two substrates of this enzyme are CTP and D-ribitol 5-phosphate, whereas its two products are diphosphate and CDP-ribitol.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is CTP:D-ribitol-5-phosphate cytidylyltransferase. Other names in common use include CDP ribitol pyrophosphorylase, cytidine diphosphate ribitol pyrophosphorylase, ribitol 5-phosphate cytidylyltransferase, and cytidine diphosphoribitol pyrophosphorylase. This enzyme participates in pentose and glucuronate interconversions.
References
- Shaw DRD (1962). "Pyrophosphorolysis and enzymic synthesis of cytidine diphosphate glycerol and cytidine diphosphate ribitol". Biochem. J. 82: 297–312. PMC 1243453. PMID 13911452. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1243453.
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